The open index of psychedelic research

Sustained pharmacodynamic effects of S-ketamine on cortical excitability and resting-state brain activity: A randomized, placebo-controlled trial.

de Cuba CMKE, de Goede AA, van Mechelen JC +9

Multi-metric evaluations of acute psychedelic effects on fMRI brain entropy.

McCulloch DE, Olsen AS, Ozenne B +6

Haemodynamic effects of ketamine in the paediatric cardiac intensive care unit: insights from high-fidelity physiologic data.

Loomba RS, Ewing K, Yao A +4

Development and Validation of a Sensitive LC-MS/MS Method for Quantifying N-Nitroso-Ketamine in Ketamine Hydrochloride Injections

Maddike RR, Kothamasu SB

Unintentional ingestion of recreational drugs among young children, 2000-2024.

Uskovich K, Hays HL, Badeti J +4

Cardiovascular effects associated with acute recreational drug toxicity presentations to the emergency department: a European drug emergencies network (Euro-DEN plus) study.

van den Busken WJ, Dines AM, Eyer F +9

Psychedelics and autism spectrum disorder: Mechanistic insights, translational evidence and ethical challenges.

Claudino Dos Santos JC, Bolan SJ, Lodetti G +3

Esketamine improves postoperative sleep quality in thoracic surgery patients with preoperative sleep disturbance: a randomized controlled trial.

Wang X, Wang H, Luo H

Music in Psychedelic- and Ketamine-Assisted Therapy: A Curated Evidence Map, 1967–2026

Alvear, Michael

Synthesis and Biological Evaluation of 4‑Bromo-<i>N,N-</i>dimethyltryptamine (4-Br-DMT): A Synthetic Building Block for Future Analog Development.

Bray E, Glatfelter GC, Maitland AD +5

Blocking 5-HT2B receptors abolishes psilocybin's efficacy in the rat forced swim test.

Seillier L, Seillier A, Zvolska MA +1

Protective Effects of Gallic Acid on Oxidative and Inflammatory Markers in the Hippocampus and Prefrontal Cortex of a Ketamine-Induced Schizophrenia-like Model.

Arslan AO, Cetin I, Yis OM +2

Real-world effectiveness and safety of intranasal esketamine for treatment-resistant depression: Data from the enTRD registry.

Preiss M, Popper V, Faber LHC +8

Network pharmacology and experimental verification to explore the therapeutic mechanism of esketamine in postoperative cognitive dysfunction.

Zhan Y, Liu S, Li Y +1

Discovery of VU6066098: A Selective and CNS-Penetrant mGlu<sub>2</sub> NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

Coleman JS, Capstick RA, Chang S +14

Using Small Area Estimation to Improve State Estimates of Psychedelic Use in the United States

Bolus versus Continuous Infusion of Esketamine for Prevention of Postpartum Depression After Caesarean Delivery: A Randomized, Double-Blind, Controlled Trial.

Yang J, Yan Q, Zhang T +5

Structural basis of opioid receptor activation by PCP and ketamine.

Jiang Q, Han J, Fine EJ +16

The Effects of Serotonergic systems on Cognitive Flexibility and Perseverative Thinking: a comparison between SSRI, classical psychedelics, and acute tryptophan depletion in a Multilevel Meta-Analysis

Basch R, Cohen M, Peled-Avron L

Discharge Readiness After Propofol with or without Esketamine for Flexible Bronchoscopy: A Randomized Non-Inferiority Trial.

Zhang X, Chen L, Chen Z +5

Decoding the serotonin-alcohol crosstalk: the role of central serotonergic dysregulation in alcohol use disorder.

Zaniewska M

Non-adherence to registration further undermines the methodologically weak Stanford University Magnesium-Ibogaine Study.

Gorman DM

Politically Salient Events May Modulate Effects of Naturalistic Psychedelic Use on Support for Partisan Violence.

Simonsson O, Hendricks PS, Osika W +1

Current clinical status of perioperative comfort therapy in pediatric anesthesia in China: a national cross-sectional survey.

Shen J, Yang L, Hou W +3