The open index of psychedelic research

Open datasets, papers, preregistrations, and trials from across psychedelic science.

11,281 records6 sources
Showing 1,345–1,368 of 11,281
ArticleKetamine

Esketamine alleviates trigeminal neuralgia and anxiety-like behaviors in mice by inhibiting RIPK1/RIPK3/MLKL-mediated necroptosis.

Dong R, Liu J, Shen Y +6

Europe PMC2026
ArticleDMT

Computational spirits: a neuroscientific account of psychedelic entity encounters.

Mago J, Deane G, Sandved-Smith L +7

Europe PMC2026
ArticlePsilocybin

Prenatal stress, excitatory-inhibitory imbalance, and ADHD risk: a hypothesis-driven perspective on psilocybin-induced neuroplasticity.

Ahmadian-Moghadam S, Roshan-Milani S, Saboory E

Europe PMC2026
ArticleKetamine

Letter to the Editor: Esketamine in treatment-resistant depression: Beyond symptom reduction toward psychopathological network reorganization.

Baharuddin B, Setyaningrum RH, Handayani L +2

Europe PMC2026
ArticleKetamine

Response to: Commentary on "Long-term treatment with esketamine nasal spray in patients with treatment resistant depression: Results from the ESCAPE-LTE study".

Reif A, Anıl Yağcıoğlu AE, Bitter I +11

Europe PMC2026
ArticleMDMA

Dataset of illicit drug consumption during and post COVID-19 through wastewater in a city of Chile.

Reis AS, Corthorn F, Navarro P +4

Europe PMC2026
ArticlePsilocybin

Correction to: Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.

Reid MJ, Kettner H, Blanken TF +2

Europe PMC2026
ArticlePsychedelics

Return of the sacred: Psychiatry's evolving relationship with spirituality.

Bhatti O, Latifi MQ

Europe PMC2026
PreprintPsychedelics

One-shotted: Psychedelic insights are uniquely intense, meaningful, and ineffable

Pogliani A, Zachary A, Hall L +3

Europe PMC2026
PreregistrationPsychedelics

Psychedelic Therapists and Personal Experience With Psychedelics: A Scoping Review of the Empirical Literature and Considerations for Psychedelic Experiential Therapist Training

OSF2026
ArticlePsilocybin

Phylogenomic systematics of <i>Lanmaoa</i> (Boletaceae) reveals cryptic diversity, resolves global evolutionary relationships, and suggests a novel psychoactive lineage.

Domnauer C, Dentinger BTM

Europe PMC2026
ArticlePsychedelics

Simultaneous use of cannabis with other drugs: Identifying latent classes in a sample of Canadians.

Farrelly KN, Wardell JD

Europe PMC2026
ArticlePsilocybin

Classic Psychedelics for Chronic Pain: A Critical Review of the Literature and Practical Advice for Clinicians.

Boehnke KF, Pouyan N, Aday JS

Europe PMC2026
ArticlePsilocybin

Current status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitus.

Lu S, Zhang Z, Xue X +7

Europe PMC2026
ArticlePsilocybin

Changes in anxiety, quality of life, and functioning following psilocybin-assisted therapy in veterans with treatment-resistant depression.

Kelly CM, Fradet M, Bostian CM +5

Europe PMC2026
PreprintMDMA

MDMA-Assisted Therapy for Social Anxiety Disorder: A Randomized, Open-label, Wait-list Controlled Trial

Luoma JB, Lear MK, Pilecki B +9

Europe PMC2026
ArticleKetamine

Approaches to ketamine-assisted couple therapy.

Avruch DO

Europe PMC2026
ArticleMDMA

Emergence of synthetic drugs in South America: insights from Brazil, Chile, and Colombia.

Bórquez I, Pantaleão B, Brogim G +3

Europe PMC2026
ArticleKetamine

Multimodal opioid-free anesthesia containing esketamine versus opioid-based anesthesia: a systematic review and meta-analysis.

Fang Y, Gao M, Wang X +8

Europe PMC2026
ArticleKetamine

The Comparative Sensitivity to Ketamine-Induced Neuronal Death in Juvenile and Adult Rats.

Sarkar S, Gamboa da Costa G, Woodling K +3

Europe PMC2026
ArticleMDMA

Comparison of acute effects of 3,4-methylenedioxymethamphetamine (MDMA) with and without a supplemental booster dose in healthy participants: a double-blind, randomized, placebo-controlled, crossover study.

Humbert-Droz M, Becker AM, Valenta J +6

Europe PMC2026
ArticlePsilocybin

Substance-induced manic psychosis in which delusions were corroborated by a chatbot - case report.

Shah S, Morrin H

Europe PMC2026
ArticlePsychedelics

Psychedelic treatments and general hospital psychiatry: Emerging themes and future directions.

Hales S, King F 4th, Huffman J

Europe PMC2026
ArticleIbogaine

Clinical improvement following an integrative iboga microdosing protocol in post-concussive and hypoxic brain injury syndromes: a case series.

Tabaac BJ, Carhart-Harris RL, Yung T

Europe PMC2026