The open index of psychedelic research

Open datasets, papers, preregistrations, and trials from across psychedelic science.

11,281 records6 sources
Showing 1,609–1,632 of 11,281
ArticleLSD

Neuroplastic white matter changes in patients with major depression following lysergic acid diethylamide treatment.

Avram M, Menegaux A, Müller F +7

Europe PMC2026
ArticleKetamine

Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.

Wang L, Zhou J, Liu Q +3

Europe PMC2026
ArticlePsilocybin

The magic of mushrooms: psilocybin influences behavior in the mangrove rivulus fish, <i>Kryptolebias marmoratus</i>.

Forsyth D, Faraone N, Lamarre SG +1

Europe PMC2026
ArticleKetamine

Esketamine attenuated sepsis-induced organ injury in mice via the TGF-β-Smad3 signaling pathway.

Haolan, Wang Y, Gao Y +5

Europe PMC2026
ProjectPsychedelics

On the meaning of ‘plasticity’ in neuroscience and mental health research and its relation to the action of psychedelic therapy

OSF2026
ArticleKetamine

Effects of Esketamine on Postoperative Sleep Quality: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Zhao J, Yan Y, Wang X +2

Europe PMC2026
ArticleMDMA

Severe Hyponatremic Encephalopathy Induced by Unsupervised "Therapeutic" 3,4-Methylenedioxymethamphetamine Use in a 55-Year-Old Woman: A Diagnostic Pitfall.

Woitrin PH, Lievens P

Europe PMC2026
ArticleKetamine

Effects of ketamine on sleep and circadian rhythmicity in major depressive disorder and bipolar disorder: A systematic review.

Boesjes R, Oosterveld C, Kamphuis J +3

Europe PMC2026
ArticleKetamine

The Effect of Intraoperative Infusion of Different Doses of Esketamine on the Quality of Recovery in Elderly Patients Undergoing Knee Arthroplasty.

Fang C, Hu Z, Lv G +7

Europe PMC2026
ArticleKetamine

Esketamine-led opioid-free anaesthesia reduces postoperative pulmonary complications in bariatric surgery patients: a prospective randomized controlled trial.

Sun HL, Liu HY, Jiang CQ +7

Europe PMC2026
PreregistrationKetamine

Evaluation of mortality following ketamine exposure in Drosophila melanogaster

OSF2026
ArticleMDMA

Glutathione as a Potential Neuroprotectant Against MDMA-Induced Oxidative Stress, Neuroinflammation, and Apoptosis in the Rat Brain.

Akano OP, Olatinwo G, Hamed MA +3

Europe PMC2026
ArticlePsilocybin

Human brain changes after first psilocybin use.

Lyons T, Spriggs M, Kerkelä L +20

Europe PMC2026
TrialKetamine

Ketamine and Dexmedetomidine for Delirium in Joint Arthroplasty

ClinicalTrials.gov2026
ArticleKetamine

Pilot study on esketamine response in treatment-resistant depression: impact of pharmacogenetic, clinical, and demographic variables.

Krivosova M, Marcatili M, Guerrera G +8

Europe PMC2026
TrialKetamine

The Effect of a Single Intravenous Injection of Esketamine During Cesarean Section on Postoperative Pruritus in Patients With Intrahepatic Cholestasis of Pregnancy

ClinicalTrials.gov2026
ArticlePsilocybin

Prevalence and Reasons for Microdosing Cannabis, Psilocybin, LSD, and MDMA Among U.S. Adults.

Yang KH, Satybaldiyeva N, Kepner W +3

Europe PMC2026
ArticleKetamine

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial.

Wilkinson ST, Kitay BM, Macaluso M +10

Europe PMC2026
PreprintDMT

Multimodal autonomic arousal tracks dose-dependent affective dynamics during the acute effects of DMT

D’Amelio TA, Garbagnoli TG, Cuello JR +10

Europe PMC2026
PreprintMDMA

A Systematic Review of MDMA’s Effects on Social Cognition in Placebo-Controlled Trials

Burmester V, Nutt D, Aggett L +5

Europe PMC2026
ArticlePsychedelics

Anything that helps: cancer patient and carer perspectives on psychedelic-assisted therapy.

Wech A, Akroyd A, Clayden C +1

Europe PMC2026
ArticleKetamine

Effect of Different Doses of Esketamine on the Propofol Effect-Site Concentration Required to Suppress Cervical Dilation-Associated Movement During Hysteroscopy: A Prospective, Randomised, Controlled, Parallel-Group Dose-Response Trial.

Shen Y, Yin L, Xu S +2

Europe PMC2026
PreprintPsychedelics

Mystical Experiences, Psychosis, and Psychedelics: A Case Series on Meditation and Psychedelic-Induced Altered States

Raj G

Europe PMC2026
ArticlePsychedelics

Regulatory context for protocol amendments and public reporting in psychedelic trials.

Swieczkowski D, Kwaśny A, Cubała WJ

Europe PMC2026