The open index of psychedelic research

Intraoperative Esketamine to Reduce Postoperative Pain and Opioid Consumption in Bariatric Surgery: A Systematic Review and Meta-Analysis.

Khalifa MA, Altbali SM, Youssef MA +3

Intranasal esketamine in treatment-resistant depression: long-term dosing patterns and clinical outcomes in a 5-year observational study.

Cuomo A, McIntyre R, Koukouna D +7

Comparative Medico-Legal Frameworks for Psilocybin Regulation: A March 2026 Update

Brinzei OV

Processed Data - Single-nucleus transcriptomics reveals time-dependent and cell-type-specific effects of psilocybin on gene expression

Liao, Clara, O'Farrell, Ethan, Weiner, Amanda +5

Psilocybin restores behavioral and neuroplastic deficits induced by chronic stress in rats.

Bysiek A, Szpręgiel I, Wojtas A +8

Management of Treatment-Resistant Depression: An Updated Narrative Review of Current and Emerging Treatments.

Berlin Viniegra JP

Analysis Code and Results: Granger-Predictive Influence Pipeline Across Five Pharmacological fMRI Datasets (LSD, Psilocybin, DMT, Ketamine, Propofol)

malone, ryan

Psychedelics and Autism Therapy: A Review of Current Research and Future Directions.

Gondi CS, Gnanamony M, Gondi TP +2

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

Anxiety sensitivity and substance use disorders: Associations across multiple drug classes and tests of a transdiagnostic mechanism.

Wesner E, Pavuluri A, Schmidt B +1

Beyond the Reducing Valve: Towards a Computational Neurophenomenology of Altered States via Deep Neural Networks

Suzuki K

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Evaluating the potential risk of ketamine-induced hepatotoxicity in the treatment of mood and anxiety disorders: A systematic review.

Lovell GFM, Vasudeva S, Orsini DK +6

Psilocybin reshapes cortical inhibition through selective interneuron recruitment

Davoudian PA, Jiang Q, Knox CA +9

Esketamine in treatment-resistant depression with and without comorbid borderline personality disorder: A real-world longitudinal study of suicidal ideation and self-harm.

Raffone F, Mazzoni F, De Ciechi A +6

The entactogen MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") disrupts helping behaviour while reinforcing electrophysiological indicators of potentially associated synaptic plasticity in male Sprague-Dawley rats.

Sáez-Briones P, Silva-Rodríguez A, Morales-Vidal M +10

Substance use predictors of arrest and self-reported criminal behavior in the United States: The role of psychedelics and rarely used drugs.

Norris JJ

Ketamine and Esketamine in Obsessive-Compulsive Disorder: A Scoping Review of Clinical and Mechanistic Evidence.

Marmureanu M, Besoiu MV, Dionisie V +4

The Emerging Neurobiology of Psychedelics: Critical Periods, Metaplasticity, and Extracellular Matrix Remodeling.

Dölen G, Wilkinson ML

Cost-effectiveness of esketamine versus alternative treatment strategies for treatment-resistant depression in Hong Kong: A multi-armed modeling study.

Li Y, Chan VKY, Jit M +7

Effect of Perioperative Ketamine on Early Postpartum Depressive Symptoms Following Cesarean Section: A Meta-Analysis.

Siu S, Hsin P, Simon S +5

Erratum: Effect of opioid sparing anesthesia with esketamine on PONV in laparoscopic sleeve gastrectomy randomized trial.

Shi KR, Zhao M, Liu K +5

Personalized Multimodal and Opioid-Sparing Analgesia for Postoperative Pain Management: Enhancing Recovery and Addressing the Post-Discharge Gap.

Sezerano ML, Niyonkuru E

Cross-species metabolic characterization of eutylone and mechanism-based inhibition of CYP2D6 and CYP2B6 with drug interaction implications.

Lee MS, Song IS, Jang Y +5