Carhart-Harris R

University of California, San Francisco, CA, USA.

43 preprints · 77 papers · ORCID

PreprintLSD

Serotonergic psychedelics delay resting state neurovascular coupling dynamics

Mundel L, Medel V, Timmermann C +9

Europe PMC2026
PreprintKetamine

Neurite Complexity and Plasticity Markers Track Synaptic Vesicle Density in the Living Human Brain: A Multimodal PET-MRI-EEG Study

Agnorelli C, Peill J, Kurtin DL +25

Europe PMC2026
PreprintPsilocybin

Psychedelics restructure information in the human brain

Blackburne G, Liardi A, Mallaroni P +6

Europe PMC2026
ArticleLSD

LSD reconfigures cortical dynamics through faster brain rhythms and increased fractal dimension.

Subramani V, Nest T, Pascarella A +8

Europe PMC2026
ArticlePsychedelics

Moving beyond 5-HT<sub>2A</sub>: language models map neurotransmitter receptors to experiential semantics.

Suresh P, Kins J, Levkovskyy L +6

Europe PMC2026
PreprintDMT

Spiral brain dynamics track the temporal unfolding of subjective intensity during the <i>N,N</i> -dimethyltryptamine experience

Sawicka G, Martínez-Marín M, Timmermann C +5

Europe PMC2026
ArticleDMT

Higher signal diversity, network dysregulation, and increased well-being under DMT administration: An EEG study.

Kroupi E, Araujo H, Oosterveld C +5

Europe PMC2026
PreprintPsychedelics

Tales of the unexpected: psychedelic trial design solutions

Carhart-Harris R, Lucas WA, Pasquini L +4

Europe PMC2026
ArticleDMT

Micro-phenomenology of immersion and perceived presences under DMT.

Sanders JW, Millière R, Demšar E +4

Europe PMC2026
PreprintPsilocybin

Sex-Specific Effects of Psilocybin Versus Escitalopram on Anxiety and Anhedonia: A Bayesian Reanalysis of Antidepressant Treatment Outcomes

Frick A, Blest-Hopley G, Grin M +3

Europe PMC2026
PreprintPsychedelics

A Shared Entropic Axis Spans States of Consciousness Across Pharmacological and Clinical Conditions

Galvan Rial DS, Della Bella GA, Naci L +8

Europe PMC2026
ArticleDMT

Computational spirits: a neuroscientific account of psychedelic entity encounters.

Mago J, Deane G, Sandved-Smith L +7

Europe PMC2026
ArticlePsilocybin

Correction to: Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.

Reid MJ, Kettner H, Blanken TF +2

Europe PMC2026
PreprintPsychedelics

On the meaning of ‘plasticity’ in neuroscience and mental health research and its relation to the action of psychedelic therapy

Carhart-Harris R, Zeifman R, Pasquini L +8

Europe PMC2026
ArticlePsilocybin

Effects of psychedelic use on authoritarian attitudes revisited.

Simonsson O, Lyons T, Marks J +5

Europe PMC2026
PreprintPsychedelics

The Allostatic Reset Model (ARM) of Psychedelic Action

Lawrence D, Brouwer A, Fabiano N +2

Europe PMC2026
ArticlePsilocybin

The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression: A post hoc path analysis.

Goodwin GM, Aaronson ST, Alvarez O +23

Europe PMC2026
ArticleKetamine

Detecting neuroplastic effects induced by ketamine in healthy human subjects: A multimodal approach.

Agnorelli C, Peill J, Sawicka G +18

Europe PMC2026
ArticlePsilocybin

The combination of exercise and psychedelics for the treatment of major depressive disorder.

Fabiano N, Stubbs B, Lawrence DW +5

Europe PMC2026
PreprintPsychedelics

Dorsal-ventral precuneus gradients organise large-scale networks and track consciousness level

Lu D, Ram A, Carhart-Harris R +5

Europe PMC2026
PreprintLSD

LSD Relaxes Structural Constraints on Brain Dynamics: A Connectome Harmonic MEG Study

Subramani V, Pascarella A, Brunel J +6

Europe PMC2026
ArticlePsychedelics

Baseline Mood and "Relational Triad" Predict Acute Qualities of Psychedelic Experience.

Lipson J, Kettner H, Carhart-Harris R +1

Europe PMC2026
PreprintPsilocybin

Prospective real-world evidence of mental health outcomes following supervised psilocybin services within Oregon’s state-regulated model

Gow A, Shih E, Reid R +5

Europe PMC2026
ArticleDMT

A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial.

Erritzoe D, Barba T, Benway T +15

Europe PMC2026
PreprintLSD

LSD Reconfigures Cortical Dynamics Through Faster Brain Rhythms and Increased Fractal Dimension

Subramani V, Nest T, Pascarella A +8

Europe PMC2026
ArticleDMT

DMT-Induced Shifts in Criticality Correlate with Self-Dissolution.

Irrmischer M, Aqil M, Luan L +5

Europe PMC2026
PreprintPsilocybin

The entropic brain today

Carhart-Harris R

Europe PMC2025
PreprintPsilocybin

Defining ‘psychedelic’

Ostrand A, Nour M, Timmermann C +7

Europe PMC2025
ArticlePsilocybin

Correction: Short- and long-term modulation of rat prefrontal cortical activity following single doses of psilocybin.

Purple RJ, Gupta R, Thomas CW +5

Europe PMC2025
ArticlePsilocybin

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness.

Alnagger NLN, Cardone P, Martial C +15

Europe PMC2026
ArticlePsychedelics

Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology.

Shinozuka K, Jerotic K, Mediano P +4

Europe PMC2025
ArticlePsilocybin

Negative affective bias in depression following treatment with psilocybin or escitalopram - a secondary analysis from a randomized trial.

Martens MAG, Cunha BG, Erritzoe D +3

Europe PMC2025
ArticleMDMA

Efficacy, all-cause discontinuation, and safety of serotonergic psychedelics and MDMA to treat mental disorders: A living systematic review with meta-analysis.

Højlund M, Kafali HY, Kırmızı B +33

Europe PMC2025
ArticlePsychedelics

Eigenmodes of the deep unconscious: the neuropsychology of Jungian archetypes and psychedelic experience.

McGovern H, Aqil M, Atasoy S +1

Europe PMC2025
ArticlePsilocybin

Corrigendum to "The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression" [Journal of Affective Disorders, Volume 372 (2025), Pages 523-532].

Goodwin GM, Aaronson ST, Alvarez O +28

Europe PMC2026
PreprintPsychedelics

Cross-species mapping of psychedelic gene expression reveals links to the 5HT2A receptor, cortical layers, and human accelerated regions

McConnell P, Raffety J, Li A +6

Europe PMC2025
PreprintPsilocybin

Blunted psychedelic drug effects in older adults

Aday JS, Carhart-Harris R, Boehnke KF

Europe PMC2025
PreprintPsilocybin

Blunted psychedelic drug effects in older adults

Aday JS, Carhart-Harris R, Boehnke KF

Europe PMC2025
ArticlePsychedelics

Validation of the Imperial Psychedelic Predictor Scale - CORRIGENDUM.

Angyus M, Osborn S, Haijen E +5

Europe PMC2025
ArticlePsilocybin

Short- and long-term modulation of rat prefrontal cortical activity following single doses of psilocybin.

Purple RJ, Gupta R, Thomas CW +5

Europe PMC2025
PreprintPsilocybin

Psychedelic Therapy, Positive Emotional Experiences, and the Central Role of Self-Compassion

Zeifman R, Danias G, Agin-Liebes G +6

Europe PMC2025
ArticlePsilocybin

Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in a psilocybin retreat.

Blest-Hopley G, Pasculli G, Ruffell SGD +7

Europe PMC2025
ArticlePsilocybin

Perturbing whole-brain models of brain hierarchy: An application for depression following pharmacological treatment.

Socoró-Garrigosa M, Perl YS, Kringelbach ML +5

Europe PMC2025
ArticlePsilocybin

Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings.

Calnan M, Blest-Hopley G, Busch C +6

Europe PMC2025
ArticlePsilocybin

Single-dose (10 mg) psilocybin reduces symptoms in adults with obsessive-compulsive disorder: A pharmacological challenge study.

Pellegrini L, Fineberg NA, O'Connor S +11

Europe PMC2025
ArticlePsilocybin

Correction: Dissociable effects of psilocybin and escitalopram for depression on processing of musical surprises.

Harding R, Singer N, Wall MB +5

Europe PMC2025
ArticlePsilocybin

The effects of psilocybin therapy versus escitalopram on cognitive bias: A secondary analysis of a randomized controlled trial.

Henry J, Giribaldi B, Nutt DJ +3

Europe PMC2025
PreprintDMT

Micro-phenomenology of immersion and perceived presences under DMT

Sanders JW, Millière R, Demšar E +3

Europe PMC2025
PreprintKetamine

Detecting neuroplastic effects induced by ketamine in healthy human subjects: a multimodal approach

Agnorelli C, Peill J, Sawicka G +16

Europe PMC2025
ArticlePsilocybin

Dissociable effects of psilocybin and escitalopram for depression on processing of musical surprises.

Harding R, Singer N, Wall MB +5

Europe PMC2025
ArticlePsychedelics

Decreased CO&lt;sub&gt;2&lt;/sub&gt; saturation during circular breathwork supports emergence of altered states of consciousness.

Havenith MN, Leidenberger M, Brasanac J +12

Europe PMC2025
ArticlePsilocybin

Neuroplasticity and psychedelics: A comprehensive examination of classic and non-classic compounds in pre and clinical models.

Agnorelli C, Spriggs M, Godfrey K +8

Europe PMC2025
ArticleLSD

The Role of the Dorsolateral Prefrontal Cortex in Ego Dissolution and Emotional Arousal During the Psychedelic State.

Coleman CR, Shinozuka K, Tromm R +7

Europe PMC2025
PreprintLSD

LSD reconfigures the frequency-specific network landscape of the human brain

Shinozuka K, Rosso M, Coleman CR +8

Europe PMC2025
PreprintPsilocybin

The effects of psilocybin therapy versus escitalopram on cognitive bias: A secondary analysis of a randomized controlled trial

Henry J, Giribaldi B, Nutt DJ +3

Europe PMC2025
ArticleDMT

Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT).

Piccinini JI, Sanz Perl Y, Pallavicini C +6

Europe PMC2025
PreprintPsilocybin

Psychedelics Align Brain Activity with Context

Stoliker D, Novelli L, Khajehnejad M +16

Europe PMC2025
ArticlePsilocybin

Psilocybin for disorders of consciousness: A case-report study.

Cardone P, Núñez P, Alnagger NLN +5

Europe PMC2025
ArticlePsilocybin

A Field-Wide Review and Analysis of Study Materials Used in Psilocybin Trials: Assessment of Two Decades of Research.

Yaden DB, Graziosi M, Owen AM +39

Europe PMC2025
ArticleDMT

Can psychedelic use benefit meditation practice? Examining individual, psychedelic, and meditation-related factors.

Jiwani Z, Goldberg SB, Stroud J +7

Europe PMC2025
PreprintDMT

DMT-induced shifts in criticality correlate with ego-dissolution

Irrmischer M, Aqil M, Luan L +5

Europe PMC2025
ArticlePsilocybin

Study Protocol for 'PsilOCD: A Pharmacological Challenge Study Evaluating the Effects of the 5-HT2A Agonist Psilocybin on the Neurocognitive and Clinical Correlates of Compulsivity'.

O'Connor S, Godfrey K, Reed S +17

Europe PMC2025
ArticleLSD

LSD flattens the hierarchy of directed information flow in fast whole-brain dynamics.

Shinozuka K, Tewarie PKB, Luppi A +7

Europe PMC2025
PreprintPsilocybin

Perturbing whole-brain models of brain hierarchy: an application for depression following pharmacological treatment

Socoró Garrigosa M, Sanz Perl Y, Kringelbach ML +3

Europe PMC2025
PreprintPsilocybin

Brain dynamics of classical psychedelics show paradoxical hierarchical flattening with increased complexity

Vohryzek J, Garcia Guzman E, Kringelbach ML +8

Europe PMC2024
ArticlePsilocybin

The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.

Goodwin GM, Aaronson ST, Alvarez O +28

Europe PMC2025
PreprintLSD

The Role of the Dorsolateral Prefrontal Cortex in Ego Dissolution and Emotional Arousal During the Psychedelic State

Coleman CR, Shinozuka K, Tromm R +7

Europe PMC2024
ArticlePsilocybin

Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology.

Shinozuka K, Jerotic K, Mediano P +4

Europe PMC2024
ArticlePsilocybin

An investigation of acute physiological and psychological moderators of psychedelic-induced personality change among healthy volunteers.

Godfrey K, Weiss B, Zhang X +5

Europe PMC2025
ArticlePsilocybin

Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.

Reid MJ, Kettner H, Blanken TF +2

Europe PMC2024
ArticlePsilocybin

Examining differences in the effects and contexts of naturalistic psilocybin use for White participants vs. Participants of Color: A longitudinal online survey study.

Jones G, Lowe MX, Nayak S +5

Europe PMC2025
PreprintPsilocybin

Human brain changes after first psilocybin use

Lyons T, Spriggs M, Kerkelä L +20

Europe PMC2024
ArticlePsychedelics

Validation of the imperial psychedelic predictor scale.

Angyus M, Osborn S, Haijen E +5

Europe PMC2024
ArticlePsilocybin

Effect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial.

Erritzoe D, Barba T, Greenway KT +9

Europe PMC2024
ArticlePsilocybin

Within-subject comparison of near-death and psychedelic experiences: acute and enduring effects.

Martial C, Carhart-Harris R, Timmermann C

Europe PMC2024
PreprintDMT

Can Psychedelic Use Benefit Meditation Practice? Examining Individual, Psychedelic, and Meditation-Related Factors

Jiwani Z, Goldberg SB, Stroud J +7

Europe PMC2024
PreprintPsilocybin

A virtual clinical trial of psychedelics to treat patients with disorders of consciousness

Alnagger NL, Cardone P, Martial C +15

Europe PMC2024
ArticlePsilocybin

Longitudinal experiences of Canadians receiving compassionate access to psilocybin-assisted psychotherapy.

de la Salle S, Kettner H, Thibault Lévesque J +8

Europe PMC2024
ArticlePsilocybin

Psilocybin desynchronizes the human brain.

Siegel JS, Subramanian S, Perry D +30

Europe PMC2024
ArticlePsychedelics

Interrupting the Psychedelic Experience Through Contextual Manipulation to Study Experience Efficacy.

Roseman L, Erritzoe D, Nutt D +2

Europe PMC2024
ArticlePsilocybin

Study protocol for "Psilocybin in patients with fibromyalgia: brain biomarkers of action".

Bornemann J, Close JB, Ahmad K +6

Europe PMC2024
PreprintLSD

LSD flattens the hierarchy of directed information flow in fast whole-brain dynamics

Shinozuka K, Tewarie PK, Luppi A +7

Europe PMC2024
ArticlePsilocybin

Psychedelics and the 'inner healer': Myth or mechanism?

Peill J, Marguilho M, Erritzoe D +5

Europe PMC2024
ArticlePsilocybin

Effects of discontinuation of serotonergic antidepressants prior to psilocybin therapy versus escitalopram for major depression.

Erritzoe D, Barba T, Spriggs MJ +3

Europe PMC2024
ArticlePsychedelics

The Relationship Between Changes in Mindfulness and Subsequent Changes in Well-Being Following Psychedelic Use: Prospective Cohort Study.

Jones G, Herrmann F, Bear A +2

Europe PMC2024
ArticlePsilocybin

Predicting the outcome of psilocybin treatment for depression from baseline fMRI functional connectivity.

Copa D, Erritzoe D, Giribaldi B +3

Europe PMC2024
ArticlePsilocybin

Psychedelics and sexual functioning: a mixed-methods study.

Barba T, Kettner H, Radu C +6

Europe PMC2024
PreprintDMT

Transient destabilization of whole brain dynamics induced by DMT

Piccinini JI, Perl YS, Pallavicini C +6

Europe PMC2024
ArticlePsychedelics

Interactions between classic psychedelics and serotonergic antidepressants: Effects on the acute psychedelic subjective experience, well-being and depressive symptoms from a prospective survey study.

Barbut Siva J, Barba T, Kettner H +4

Europe PMC2024
ArticlePsilocybin

Assessing expectancy and suggestibility in a trial of escitalopram v. psilocybin for depression.

Szigeti B, Weiss B, Rosas FE +3

Europe PMC2024
ArticleDMT

5-MeO-DMT: An atypical psychedelic with unique pharmacology, phenomenology &amp; risk?

Dourron HM, Nichols CD, Simonsson O +3

Europe PMC2025
PreprintPsilocybin

Synergistic, Multi-level Understanding of Psychedelics: Three Systematic Reviews and Meta-analyses of Their Pharmacology, Neuroimaging and Phenomenology

Shinozuka K, Jerotic K, Mediano P +4

Europe PMC2023
ArticleDMT

Optimized infusion rates for N,N-dimethyltryptamine to achieve a target psychedelic intensity based on a modeling and simulation framework.

Eckernäs E, Koomen J, Timmermann C +3

Europe PMC2023
ArticlePsilocybin

Psilocybin therapy for treatment resistant depression: prediction of clinical outcome by natural language processing.

Dougherty RF, Clarke P, Atli M +10

Europe PMC2025
ArticlePsychedelics

The difference between 'placebo group' and 'placebo control': a case study in psychedelic microdosing.

Szigeti B, Nutt D, Carhart-Harris R +1

Europe PMC2023
ArticlePsilocybin

Assessing the risk of symptom worsening in psilocybin-assisted therapy for depression: A systematic review and individual participant data meta-analysis.

Simonsson O, Carlbring P, Carhart-Harris R +5

Europe PMC2023
ArticlePsychedelics

Pattern breaking: a complex systems approach to psychedelic medicine.

Hipólito I, Mago J, Rosas FE +1

Europe PMC2023
ArticleLSD

A whole-brain model of the neural entropy increase elicited by psychedelic drugs.

Herzog R, Mediano PAM, Rosas FE +5

Europe PMC2023
PreprintDMT

Psychological and physiological effects of extended DMT

Luan LX, Eckernäs E, Ashton M +10

Europe PMC2023
PreprintMDMA

Focusing on the negative: cases of long-term negative psychological responses to psychedelics

Bremler R, Katati N, Shergill P +2

Europe PMC2023
ArticleDMT

N,N-dimethyltryptamine affects electroencephalography response in a concentration-dependent manner-A pharmacokinetic/pharmacodynamic analysis.

Eckernäs E, Timmermann C, Carhart-Harris R +2

Europe PMC2023
ArticleLSD

LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics.

Ruffini G, Damiani G, Lozano-Soldevilla D +7

Europe PMC2023
ArticlePsilocybin

Changes in music-evoked emotion and ventral striatal functional connectivity after psilocybin therapy for depression.

Shukuroglou M, Roseman L, Wall M +3

Europe PMC2023
PreprintPsychedelics

Predictors Of Hallucinogen Persisting Perception Disorder Symptoms, Delusional Ideation And Magical Thinking Following Naturalistic Psychedelic Use

Zhou K, De Wied D, Carhart-Harris R +1

Europe PMC2022
ArticlePsilocybin

A Bayesian Reanalysis of a Trial of Psilocybin versus Escitalopram for Depression.

Nayak SM, Bari BA, Yaden DB +7

Europe PMC2023
PreprintLSD

A mechanistic model of the neural entropy increase elicited by psychedelic drugs

Herzog R, Mediano PA, Rosas FE +5

Europe PMC2022
PreprintPsilocybin

Evidence for tolerance in psychedelic microdosing from the self-blinding microdose trial

Baumann S, Carhart-Harris R, Nutt D +2

Europe PMC2022
ArticlePsilocybin

Effects of classic psychedelic drugs on turbulent signatures in brain dynamics.

Cruzat J, Perl YS, Escrichs A +10

Europe PMC2022
PreprintPsilocybin

Psilocybin Therapy for Treatment Resistant Depression: Prediction of Clinical Outcome by Natural Language Processing

Dougherty RF, Clarke P, Alti M +10

Europe PMC2022
ArticleDMT

Population pharmacokinetic/pharmacodynamic modeling of the psychedelic experience induced by N,N-dimethyltryptamine - Implications for dose considerations.

Eckernäs E, Timmermann C, Carhart-Harris R +2

Europe PMC2022
PreprintPsilocybin

Brain dynamics predictive of response to psilocybin for treatment-resistant depression

Vohryzek J, Cabral J, Lord L +6

Europe PMC2022
ArticlePsilocybin

Effects of psilocybin versus escitalopram on rumination and thought suppression in depression.

Barba T, Buehler S, Kettner H +6

Europe PMC2022
PreprintLSD

LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics

Ruffini G, Damiani G, Lozano-Soldevilla D +7

Europe PMC2022
ArticlePsilocybin

The Watts Connectedness Scale: a new scale for measuring a sense of connectedness to self, others, and world.

Watts R, Kettner H, Geerts D +9

Europe PMC2022
ArticleDMT

Phenomenology and content of the inhaled N, N-dimethyltryptamine (N, N-DMT) experience.

Lawrence DW, Carhart-Harris R, Griffiths R +1

Europe PMC2022
PreprintDMT

Phenomenology and Content of the Inhaled N, N-Dimethyltryptamine (N, N-DMT) Experience

Lawrence DW, Carhart-Harris R, Griffiths R +1

Europe PMC2022
ArticlePsilocybin

Serotonergic psychedelic drugs LSD and psilocybin reduce the hierarchical differentiation of unimodal and transmodal cortex.

Girn M, Roseman L, Bernhardt B +3

Europe PMC2022
ArticlePsilocybin

Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression.

Murphy R, Kettner H, Zeifman R +10

Europe PMC2021
ArticleDMT

Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.

Eckernäs E, Bendrioua A, Cancellerini C +4

Europe PMC2022
ArticlePsychedelics

Self-Medication for Chronic Pain Using Classic Psychedelics: A Qualitative Investigation to Inform Future Research.

Bornemann J, Close JB, Spriggs MJ +2

Europe PMC2021