González-Maeso J

Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA. Electronic address: javier.maeso@vcuhealth.org.

González-Maeso J

Prior trauma shapes the effects of psilocybin on stress sensitization in mice.

Design of a new psychedelic quipazine analog with therapeutic efficacy and potentially fewer side effects.

Integrated 5-HT&lt;sub&gt;2A&lt;/sub&gt;-TrkB and G protein signaling in serotonergic psychedelic responses.

Reshaping human neurons.

Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice.

Integrated 5-HT <sub>2A</sub> –TrkB and G protein signaling in serotonergic psychedelic responses

Stereoselective, sex-dependent 5-HT&lt;sub&gt;2A&lt;/sub&gt; receptor modulation of cortical plasticity by MDMA in mice.

Snapshot IP&lt;sub&gt;1&lt;/sub&gt; Detection Following 5-HT&lt;sub&gt;2&lt;/sub&gt;A Receptor Stimulation in the Mouse Brain.

Dual Modulation of 5-HT&lt;sub&gt;2A&lt;/sub&gt; Receptors and SERT by α-Ethyltryptamine and Its Optical Isomers.

Quantitative phosphoproteomics uncovers the signalling dynamics of hallucinogenic psychedelics

Sex-specific role of the 5-HT&lt;sub&gt;2A&lt;/sub&gt; receptor in psilocybin-induced extinction of opioid reward.

Distinctive patterns of G protein coupling induced by the structurally similar 5-HT&lt;sub&gt;2A&lt;/sub&gt; receptor ligands ketanserin and altanserin in human prefrontal cortex.

Snapshot of 5-HT <sub>2A</sub> receptor activation in the mouse brain via IP <sub>1</sub> detection

Ethopharmacological evaluation of antidepressant-like effect of serotonergic psychedelics in C57BL/6J male mice.

Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics.

Ethopharmacological evaluation of antidepressant-like effect of serotonergic psychedelics in C57BL/6J male mice

The crosstalk between 5-HT<sub>2A</sub>R and mGluR2 in schizophrenia.

Automated Detection of Psychedelic-Induced Head-Twitch Response in Mice.

Differences across sexes on head-twitch behavior and 5-HT<sub>2A</sub> receptor signaling in C57BL/6J mice.

Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT<sub>2A</sub> Receptor Agonists in Mice.

Effects of the 5-HT<sub>2A</sub> receptor antagonist volinanserin on head-twitch response and intracranial self-stimulation depression induced by different structural classes of psychedelics in rodents.

Molecular targets of psychedelic-induced plasticity.

Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice.

Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice.

Psychedelic-like Properties of Quipazine and Its Structural Analogues in Mice.

Automated quantification of head-twitch response in mice via ear tag reporter coupled with biphasic detection.

Fully automated head-twitch detection system for the study of 5-HT<sub>2A</sub> receptor pharmacology in vivo.

Serotonin and Glutamate Interactions in Preclinical Schizophrenia Models.

Hallucinogens and Serotonin 5-HT<sub>2A</sub> Receptor-Mediated Signaling Pathways.

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice.

Preclinical models of antipsychotic drug action.

Animal models of serotonergic psychedelics.

Integrated 5-HT<sub>2A</sub>-TrkB and G protein signaling in serotonergic psychedelic responses.

Stereoselective, sex-dependent 5-HT<sub>2A</sub> receptor modulation of cortical plasticity by MDMA in mice.

Snapshot IP<sub>1</sub> Detection Following 5-HT<sub>2</sub>A Receptor Stimulation in the Mouse Brain.

Dual Modulation of 5-HT<sub>2A</sub> Receptors and SERT by α-Ethyltryptamine and Its Optical Isomers.

Sex-specific role of the 5-HT<sub>2A</sub> receptor in psilocybin-induced extinction of opioid reward.

Distinctive patterns of G protein coupling induced by the structurally similar 5-HT<sub>2A</sub> receptor ligands ketanserin and altanserin in human prefrontal cortex.