Hashimoto K

Pleiotropic modulation of the gut-brain-lung axis by ketamine and its enantiomers.

Zhao X, Zhang X, Yuan S +2

Europe PMC2026

ArticleMDMA

Antibiotic-induced Microbiome Depletion Selectively Reduces Baseline Hypothalamic Oxytocin Signaling without Affecting MDMA-induced Oxytocin Response in Rats.

Yue Y, Cai Y, Murayama R +6

Europe PMC2026

Transcriptional Signatures of Mitochondrial Metabolism Predict Esketamine-Induced rACC Structural Changes in Adolescent Major Depression.

Zhou Y, Li W, Lan X +16

Intestinal γδ T17-IL-17A signaling disrupts hippocampal mitophagy in stress-induced depression and is restored by arketamine.

Han M, Xie B, Yu Y +15

Esketamine prevents postoperative sleep disturbance in patients with preoperative sleep disorders: a role for oral microbiota.

Li XY, Qiu D, Du N +3

ArticlePsychedelics

Psychedelic therapy: a paradigm shift in treating neuropsychiatric disorders.

Jin M, Ji X, Liu X +3

ArticleMDMA

Intermittent MDMA Attenuates Ovariectomy-induced Bone Loss via a Gut Microbiota-Bone Axis.

Wan X, Eguchi A, Murayama R +2

Racemic Ketamine vs Esketamine in Treatment-Resistant Depression: The Overlooked Role of Arketamine.

Tan Y, Hashimoto K

Effects of esketamine on electrophysiology and metabolic reprogramming in brain organoids: insights into antidepressant mechanisms.

Li M, Duan W, Hao X +19

Microglial BDNF modulates arketamine's antidepressant-like effects through cortico-accumbal pathways.

He L, Wang X, Luo S +8

Repeated administration of esketamine ameliorates mechanical allodynia in mice with chemotherapy-induced peripheral neuropathy: A role of gut microbiota and metabolites.

Luan WW, Gu HW, Qiu D +5

ArticleMDMA

Special issue on "Ketamine, MDMA, and psychedelics in the treatment of neuropsychiatric disorders".

Hashimoto K, Wang X, Zhang J

PreprintPsilocybin

Distinct classes of antidepressants commonly act to shape pallidal structure and function in mice

Abe Y, Sugiura Y, Maeda R +7

Ketamine and its two enantiomers in anesthesiology and psychiatry: A historical review and future directions.

Hashimoto K, Zhao M, Zhu T +2

Ketamine and its enantiomers for depression: a bibliometric analysis from 2000 to 2023.

Zhao LY, Zhang GF, Lou XJ +2

Efficacy and safety of esketamine for perioperative depression in patients undergoing elective surgery: A meta-analysis of randomized controlled trials.

Lou XJ, Qiu D, Ren ZY +3

Are "mystical experiences" essential for antidepressant actions of ketamine and the classic psychedelics?

Hashimoto K

Prophylactic effects of arketamine, but not hallucinogenic psychedelic DOI nor non-hallucinogenic psychedelic analog lisuride, in lipopolysaccharide-treated mice and mice exposed to chronic restrain stress.

Liu G, Ma L, Qu Y +5

Effects of perioperative use of esketamine on postpartum depression risk in patients undergoing cesarean section: A randomized controlled trial.

Liu QR, Zong QK, Ding LL +6

Risk of esketamine anesthesia on the emergence delirium in preschool children after minor surgery: a prospective observational clinical study.

Chen S, Yang JJ, Zhang Y +6

Arketamine for cognitive impairment in psychiatric disorders.

Hashimoto K

Rapid antidepressant-like effect of non-hallucinogenic psychedelic analog lisuride, but not hallucinogenic psychedelic DOI, in lipopolysaccharide-treated mice.

Qu Y, Chang L, Ma L +2