Li Y

College of Computer Science and Artificial Intelligence, Wenzhou University, Wenzhou, China. leee@zju.edu.cn.

57 papers · 2 preprints · ORCID

ArticleKetamine

A circuit dissection of perception-action decoupling in S-ketamine-induced hallucination-like states.

Wang D, Xu J, Wang Z +13

Europe PMC2026
ArticleKetamine

Samm50 downregulation-driven mitochondrial dysfunction triggers ferroptosis and contributes to ketamine-induced neurotoxicity and cognitive impairment.

Li Y, Dai X, Hu J +7

Europe PMC2026
ArticleKetamine

Esketamine Ameliorates Propofol-Induced Long-Term Cognitive Impairments in Juvenile Rats by Suppressing Autophagy via Activating the PI3K/Akt/mTOR Signaling Pathway.

Wang Y, Li Y, Chen Z +4

Europe PMC2026
PreprintKetamine

The Effects of Different Doses of Intravenous Esketamine on Postoperative Sleep and Chronic Pain in Patients Undergoing Thoracoscopic Lung Resection Surgery: A Randomized Controlled Trial

Li Y, Wang Y, Jin L +3

Europe PMC2026
ArticleKetamine

Effects of esketamine on postoperative delirium in adult patients: a systematic review and meta-analysis of randomized controlled trials.

Liu X, Liu C, Li Y +6

Europe PMC2026
ArticleKetamine

Interpreting Perineural Esketamine for Analgesia After Total Knee Arthroplasty: Methodological and Reporting Considerations [Letter].

Zhou Z, Li Y, Lu J

Europe PMC2026
ArticlePsilocybin

α<sub>2</sub>-Adrenergic receptor modulates 5-HT<sub>2A</sub>-mediated behavioral effects of MDMA and psilocybin in mice.

Rosado AF, Yu AL, Yang JH +13

Europe PMC2026
ArticlePsilocybin

Psilocybin reduces fear memory and restores neuroplasticity in the hippocampus and medial prefrontal cortex.

Du Y, Zhao X, Yao Y +3

Europe PMC2026
ArticleKetamine

Ketamine enhances histone H3 (Ser10) phosphorylation via JNK signaling and multi-omics profiling of the hippocampus in a psychotic-like mouse model.

Zhu XM, Li Y, Liu W +5

Europe PMC2026
ArticleKetamine

Network pharmacology and experimental verification to explore the therapeutic mechanism of esketamine in postoperative cognitive dysfunction.

Zhan Y, Liu S, Li Y +1

Europe PMC2026
ArticleKetamine

Investigation of Esketamine Administration During Surgical Procedures for the Alleviation of Postoperative Anxiety and Depression in Adolescent Patients: A Randomized Controlled Trial.

Li Y, Zhao K, Cao P +3

Europe PMC2026
ArticleDMT

Combining dance movement therapy and pharmacotherapy in adolescents with major depressive disorder: A randomized controlled study.

Liu Y, Zhang W, Sun X +5

Europe PMC2026
ArticleKetamine

Cost-effectiveness of esketamine versus alternative treatment strategies for treatment-resistant depression in Hong Kong: A multi-armed modeling study.

Li Y, Chan VKY, Jit M +7

Europe PMC2026
ArticleKetamine

Letter to editor regarding "Efficacy of esketamine after cesarean section for women with symptoms of prenatal depression: A randomized controlled trial".

Li Y, Ding X

Europe PMC2026
ArticleKetamine

Ketamine/esketamine for preventing rebound pain after peripheral nerve block: a systematic review and meta-analysis of randomized controlled trials.

Zhong L, Zhong R, Xie B +2

Europe PMC2026
ArticleKetamine

Precise perioperative assessment and anesthesia strategy for painless gastrointestinal endoscopy in high-risk cardiovascular disease patients.

Li Y, Xiao H, Zheng H +1

Europe PMC2026
ArticleKetamine

Esketamine combined with hydromorphone versus hydromorphone for post-operative patient-controlled intravenous analgesia in children: a randomized controlled trial.

Li Y, Wang L, Liu K +4

Europe PMC2026
ArticleKetamine

Subanesthetic S-ketamine prevents postoperative delirium and reduces inflammatory cytokines in older patients receiving hip fracture surgery: a randomized, controlled study.

Hou J, Wang J, Li Y +2

Europe PMC2026
ArticleKetamine

Effect of Esketamine Combined with Lidocaine on Opioid Requirements in the Elderly Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized, Double-Blind, Controlled Trial.

Xie JX, Wang X, Li Y +5

Europe PMC2026
ArticleKetamine

Immunoreactivity and distribution of Fos in the mouse brain following diverse general anesthetics.

Hu Y, Yang J, Huang J +6

Europe PMC2025
ArticleKetamine

Effects of Esketamine-Dexmedetomidine Combination on Immediate Postprocedural Oxygenation Index in Severe Pneumonia Patients Undergoing Bedside Fiberoptic Bronchoscopic Sputum Aspiration: A Prospective Randomised Controlled Trial.

Wang Y, Zhang R, Wu B +3

Europe PMC2025
ArticleKetamine

Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.

Zhao C, Liu J, Zhao S +5

Europe PMC2025
ArticleKetamine

Impact of opioid-free anesthesia on the overall benefit of analgesia score after laparoscopic cholecystectomy: protocol and statistical analysis plan for a multicenter, randomized, controlled trial.

Zhao HX, Han L, Wang D +7

Europe PMC2025
ArticleKetamine

Efficacy and Safety of Esketamine-Lidocaine for Anesthesia Induction in Elderly Patients Undergoing Elective Surgery: A Randomized Controlled Trial.

Xu J, Yuan M, Zhou T +2

Europe PMC2025
ArticleKetamine

Effects of low-dose esketamine on hypoxemia during gastroscopy in patients with moderate-to-high risk obstructive sleep apnea: protocol for a prospective, randomized, controlled trial.

Li XM, Hao SQ, Qi XR +3

Europe PMC2025
ArticleKetamine

Clinical Benefits and Challenges of Esketamine in Elderly Patients During the Perioperative Period.

Zhang S, Bai C, Xu M +4

Europe PMC2025
ArticleKetamine

A comparative study of dexmedetomidine combined with esketamine and sufentanil for sedation and analgesia in patients undergoing microwave ablation of lung tumors: A prospective single-center randomized double-blind clinical trial.

Li Y, Li Y, Zhang Y +6

Europe PMC2025
ArticleKetamine

Esketamine and Ketamine use in the Adolescent Population for Treatment Resistent Depression: A Systematic Review

Chen G, Li Y

Europe PMC2025
ArticlePsilocybin

Exploring the therapeutic potential of psychedelics in treating substance use disorders.

Li Y, Li H, Wang H +1

Europe PMC2025
ArticleKetamine

Esketamine for Preventing Catheter-Related Bladder Discomfort After Ureteroscopic Lithotripsy: A Randomized Controlled Trial.

Wang Z, Li H, Wang Y +4

Europe PMC2025
ArticleKetamine

S-ketamine facilitates motor function recovery after brachial plexus root avulsion and reimplantation in mice.

Huang R, Lin B, Yu L +7

Europe PMC2025
ArticleKetamine

Perioperative use of esketamine for the prevention of postpartum depression after cesarean section: a meta-analysis.

Li Y, Zhao K, Cao P +3

Europe PMC2025
ArticleKetamine

Effect of dexmedetomidine-assisted esketamine on hemodynamics and stress level in patients undergoing total laparoscopic hysterectomy under general anesthesia.

Ye X, Xie B, Li Y +2

Europe PMC2026
ArticleKetamine

Opioid-Free Anesthesia Improved the Quality of Recovery After Thyroidectomy Through Pre-Emptive and Preventive Analgesia: A Randomized Controlled Trial.

Zhang Y, Xian X, Wang F +5

Europe PMC2025
ArticleKetamine

Effect of the Preoperative Application of Esketamine on Stress Indicators in Paediatric Patients Undergoing Bronchoalveolar Lavage Under General Anaesthesia.

Zhang J, Zheng J, Sun X +2

Europe PMC2025
ArticleKetamine

The effect of esketamine on emergence delirium in pediatric patients undergoing general anesthesia: a meta-analysis of randomized controlled trials.

Li S, Li Y, Gao P

Europe PMC2025
ArticleLSD

Effects of intravenous propofol combined with opioids on euphoria in patients undergoing painless gastrointestinal endoscopy: protocol for a randomized double-blind placebo-controlled trial.

Yu Y, Ma Q, Du F +4

Europe PMC2025
ArticleKetamine

Effects of Esketamine Versus Remifentanil on Hemodynamics and Prognosis in Patients with Septic Shock Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial.

Li Y, Li H, Zhang F +2

Europe PMC2025
PreprintKetamine

Esketamine relieves postoperative depression and pain indicators in patients undergoing laparoscopic total hysterectomy

Jing J, Zhang M, Yin W +4

Europe PMC2025
ArticleKetamine

S-ketamine ameliorates post-stroke depression in mice via attenuation of neuroinflammation, synaptic restoration, and BDNF pathway activation.

Tian J, Xie Y, Ye S +6

Europe PMC2025
ArticleKetamine

Development and validation of machine learning models for predicting post-cesarean pain and individualized pain management strategies: a multicenter study.

Lv S, Sun N, Hao C +2

Europe PMC2025
ArticleMDMA

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine-Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms.

Li Y, Li H, Wang H +1

Europe PMC2025
ArticleKetamine

Esketamine alleviated cardiomyocyte ferroptosis induced by oxygen-glucose deprivation/reoxygenation (OGD/R) via cyclic GMP-AMP synthase interactor.

Ouyang J, Xiao W, Wu D +3

Europe PMC2025
ArticleDMT

Application of microarray patches for the transdermal administration of psychedelic drugs in micro-doses.

Fandiño OE, Hutton ARJ, Zhang C +5

Europe PMC2025
ArticleKetamine

Repeated high-dose esketamine in early postnatal rats leads to behavioural deficits with long-term modifications in white matter microstructural integrity.

Zhou L, Wang X, Cao T +3

Europe PMC2025
ArticleKetamine

Impact of different doses of esketamine on the incidence of hypotension in propofol-based sedation for colonoscopy: a randomized controlled trial.

Fu M, Sheng B, Liu R +8

Europe PMC2024
ArticleLSD

Psychedelic LSD activates neurotrophic signal but fails to stimulate neural stem cells.

Dong X, Lin H, Li Y +2

Europe PMC2024
ArticleKetamine

Effect of esketamine on serum neurotransmitters in patients with postpartum depression: a randomized controlled trial.

Jiang Q, Qi Y, Zhou M +6

Europe PMC2024
ArticleKetamine

Effect of esketamine on hypotension in women with preoperative anxiety undergoing elective cesarean section: a randomized, double-blind, controlled trial.

Qi Y, Zhou M, Dong Y +8

Europe PMC2024
ArticleKetamine

Effect of Continuous Infusion of Different Doses of Esketamine on the Bispectral Index During Sevoflurane Anesthesia: A Randomized Controlled Trial.

Ren L, Yang J, Li Y +1

Europe PMC2024
ArticleKetamine

Effect of subanesthetic dose of esketamine on postoperative pain in elderly patients undergoing laparoscopic gastrointestinal tumor Surgery:A prospective, double-blind, randomized controlled trial.

Jing Z, Han Y, Li Y +4

Europe PMC2024
ArticleKetamine

Effect of esketamine-based opioid-sparing anesthesia strategy on postoperative pain and recovery quality in patients undergoing total laparoscopic hysterectomy: A randomized controlled trail.

Liu J, Yin J, Yin J +4

Europe PMC2024
ArticleKetamine

Comparison of dexmedetomidine and a dexmedetomidine-esketamine combination for reducing dental anxiety in preschool children undergoing dental treatment under general anesthesia: A randomized controlled trial.

Xing F, Zhang TT, Yang Z +7

Europe PMC2024
ArticleKetamine

Supplemental low-dose esketamine to propofol versus propofol alone on perioperative characteristics in children undergoing surgery: a prospective randomized controlled trial.

Han D, Du X, Li Y +5

Europe PMC2024
ArticleKetamine

Effect of continuous subanesthetic esketamine infusion on postoperative fatigue in patients undergoing laparoscopic radical resection for colorectal cancer: a randomized controlled study.

Sun L, Zhao Y, Li Y +6

Europe PMC2023
ArticleKetamine

Neonatal outcomes when intravenous esketamine is added to the parturients transferred from labor analgesia to emergency cesarean section: a retrospective analysis report.

Liang Z, Zhou T, Wang M +1

Europe PMC2023
ArticleKetamine

Efficacy and Safety of a Subanesthetic Dose of Esketamine Combined with Propofol in Patients with Obesity Undergoing Painless Gastroscopy: A Prospective, Double-Blind, Randomized Controlled Trial.

Zheng L, Wang Y, Ma Q +8

Europe PMC2023
ArticleKetamine

Prenatal Exposure to General Anesthesia Drug Esketamine Impaired Neurobehavior in Offspring.

Huang R, Lin B, Tian H +2

Europe PMC2023
ArticleLSD

Lysergic acid diethylamide causes mouse retinal damage by up-regulating p-JAK1/p-STAT1.

Chen K, He X, Li C +7

Europe PMC2020