McCorvy JD

Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226.

26 papers · 1 preprint · ORCID

ArticleLSD

Deconstruction of lysergic acid diethylamide.

Basargin AG, Domokos A, Hennessey JJ +17

Europe PMC2026
ArticlePsychedelics

Serotonin Transporter Blockade Reduces the Psychedelic-Like Effects of 4-Methoxy-<i>N</i>-methyl-<i>N</i>-isopropyltryptamine and Related Analogs.

Glatfelter GC, Schalk SS, Walther D +9

Europe PMC2026
ArticleMDMA

Correction to "Next-Generation MDMA Analogue SDMA: Pharmacological and Metabolic Insights".

Kastner N, Nadal-Gratacós N, Hemmer S +17

Europe PMC2026
ArticlePsychedelics

Transforming Amino Acids into Serotonin 5-HT<sub>2A</sub> Receptor Ligands Using Photochemistry.

Beckett JOS, Buzdygon R, Nguyen S +9

Europe PMC2025
ArticleMDMA

Next-Generation MDMA Analogue SDMA: Pharmacological and Metabolic Insights.

Kastner N, Nadal-Gratacós N, Hemmer S +17

Europe PMC2025
ArticlePsychedelics

Discovery of Highly Selective 5-HT<sub>2A</sub> Agonists Using Structure-Guided Design.

Fenske TG, McKee JL, Cavalco NG +7

Europe PMC2025
ArticlePsilocybin

Serotonin 5-HT<sub>2C</sub> Receptor Signaling Analysis Reveals Psychedelic Biased Agonism.

Bonniwell EM, Alabdali R, Hennessey JJ +7

Europe PMC2025
ArticlePsychedelics

The ABCs of psychedelics: a preclinical roadmap for drug discovery.

Kwan AC, Mantsch JR, McCorvy JD

Europe PMC2025
ArticleLSD

Assessing the Potential Cardiovascular Risk of Microdosing the Psychedelic LSD in Mice.

Effinger DP, Schalk SS, King JL +6

Europe PMC2025
ArticlePsychedelics

Biased Signaling in Psychedelic Action.

Wacker D, McCorvy JD

Europe PMC2026
ArticlePsychedelics

The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation.

Aarrestad IK, Cameron LP, Fenton EM +35

Europe PMC2025
PreprintLSD

Assessing the potential cardiovascular risk of microdosing the psychedelic LSD in mice

Effinger DP, Schalk SS, King JL +5

Europe PMC2025
ArticleDMT

Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-<i>N</i>,<i>N</i>-dimethyltryptamine Analogs in Mice.

Glatfelter GC, Clark AA, Cavalco NG +9

Europe PMC2024
ArticlePsychedelics

Identification of 5-HT<sub>2A</sub> receptor signaling pathways associated with psychedelic potential.

Wallach J, Cao AB, Calkins MM +16

Europe PMC2023
ArticlePsilocybin

Beyond the 5-HT<sub>2A</sub> Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action.

Cameron LP, Benetatos J, Lewis V +7

Europe PMC2023
ArticlePsilocybin

Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala.

Kelly TJ, Bonniwell EM, Mu L +7

Europe PMC2024
ArticleLSD

Molecular insights into GPCR mechanisms for drugs of abuse.

Sanchez-Reyes OB, Zilberg G, McCorvy JD +1

Europe PMC2023
ArticleLSD

A non-hallucinogenic LSD analog with therapeutic potential for mood disorders.

Lewis V, Bonniwell EM, Lanham JK +16

Europe PMC2023
ArticlePsychedelics

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.

Vargas MV, Dunlap LE, Dong C +11

Europe PMC2023
ArticlePsychedelics

Pharmacological Mechanism of the Non-hallucinogenic 5-HT<sub>2A</sub> Agonist Ariadne and Analogs.

Cunningham MJ, Bock HA, Serrano IC +14

Europe PMC2023
ArticlePsychedelics

Bespoke library docking for 5-HT<sub>2A</sub> receptor agonists with antidepressant activity.

Kaplan AL, Confair DN, Kim K +24

Europe PMC2022
ArticleMDMA

(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice.

Rudin D, McCorvy JD, Glatfelter GC +13

Europe PMC2022
ArticlePsilocybin

Investigation of the Structure-Activity Relationships of Psilocybin Analogues.

Klein AK, Chatha M, Laskowski LJ +5

Europe PMC2021
ArticleIbogaine

A non-hallucinogenic psychedelic analogue with therapeutic potential.

Cameron LP, Tombari RJ, Lu J +26

Europe PMC2021
ArticlePsilocybin

Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin.

Sherwood AM, Halberstadt AL, Klein AK +4

Europe PMC2020
ArticleLSD

Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD).

Halberstadt AL, Chatha M, Klein AK +5

Europe PMC2020
ArticleLSD

Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775).

Brandt SD, Kavanagh PV, Twamley B +8

Europe PMC2018