Mertens LJ

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, lea.mertens@zi-mannheim.de.

16 papers · ORCID

ArticlePsilocybin

Long-Term Efficacy of Psilocybin with Adjunct Psychotherapy in Treatment-Resistant Major Depression: 6- and 12-Month Naturalistic Follow-Up of a Phase 2b Trial.

Mertens LJ, Betzler F, Brand M +24

Europe PMC2026
ArticlePsilocybin

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression: The EPISODE Randomized Clinical Trial.

Mertens LJ, Koslowski M, Betzler F +23

Europe PMC2026
ArticlePsychedelics

Psychedelics: The pathway to implementation in the European healthcare systems.

Gründer G, Mertens LJ, Spangemacher M +2

Europe PMC2026
ArticlePsychedelics

Common factors in altered states: Understanding psychedelic therapy through the lens of Grawe's general change mechanisms.

Wolff M, Rutrecht H, Mertens LJ +6

Europe PMC2025
ArticlePsilocybin

Compassionate use of psilocybin for treatment-resistant depression in Germany.

Gründer G, Mertens LJ, Jungaberle A +2

Europe PMC2026
ArticlePsilocybin

A Field-Wide Review and Analysis of Study Materials Used in Psilocybin Trials: Assessment of Two Decades of Research.

Yaden DB, Graziosi M, Owen AM +39

Europe PMC2025
ArticleKetamine

[Mechanisms of action of antidepressive pharmacotherapy: brain and mind-body and environment].

Spangemacher M, Reinwald J, Adolphi H +4

Europe PMC2025
ArticlePsilocybin

Psilocybin as a Disease-Modifying Drug—A Salutogenic Approach in Psychiatry.

Spangemacher M, Mertens LJ, Färber LV +3

Europe PMC2024
ArticlePsychedelics

Measuring psychotherapeutic processes in the context of psychedelic experiences: Validation of the General Change Mechanisms Questionnaire (GCMQ).

Wolff M, Evens R, Mertens LJ +6

Europe PMC2024
ArticlePsilocybin

Methodological challenges in psychedelic drug trials: Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) - Rationale and study design.

Mertens LJ, Koslowski M, Betzler F +9

Europe PMC2022
ArticlePsilocybin

The Acceptance/Avoidance-Promoting Experiences Questionnaire (APEQ): A theory-based approach to psychedelic drugs' effects on psychological flexibility.

Wolff M, Mertens LJ, Walter M +2

Europe PMC2022
ArticlePsychedelics

Validation of the Psychological Insight Scale: A new scale to assess psychological insight following a psychedelic experience.

Peill JM, Trinci KE, Kettner H +6

Europe PMC2022
ArticlePsilocybin

Classical Psychedelics as Therapeutics in Psychiatry - Current Clinical Evidence and Potential Therapeutic Mechanisms in Substance Use and Mood Disorders.

Mertens LJ, Preller KH

Europe PMC2021
ArticlePsychedelics

Post-Psychedelic Reductions in Experiential Avoidance Are Associated With Decreases in Depression Severity and Suicidal Ideation.

Zeifman RJ, Wagner AC, Watts R +3

Europe PMC2020
ArticlePsilocybin

Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse.

Meinhardt MW, Güngör C, Skorodumov I +2

Europe PMC2020
ArticlePsilocybin

Learning to Let Go: A Cognitive-Behavioral Model of How Psychedelic Therapy Promotes Acceptance.

Wolff M, Evens R, Mertens LJ +4

Europe PMC2020