Nichols CD

Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA, USA. cnich1@lsuhsc.edu.

24 papers · 2 preprints · ORCID

ArticlePsychedelics

Psychedelic research must be grounded in pharmacology.

Nichols CD

Europe PMC2026
ArticlePsilocybin

Psychedelics produce enduring behavioral effects and functional plasticity through mechanisms independent of structural plasticity.

Kramer HM, Hibicke M, Middleton J +3

Europe PMC2026
ArticlePsilocybin

The Selective Serotonin 5‑HT<sub>2A</sub> Receptor Agonist (<i>S</i>)‑3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents.

Jensen AA, Cecchi CR, Hibicke M +6

Europe PMC2025
ArticlePsilocybin

5-HT<sub>2A</sub> receptors: Pharmacology and functional selectivity.

Cummins BR, Billac GB, Nichols DE +1

Europe PMC2025
ArticleMescaline

History of psychedelic drug science and molecular pharmacology.

Nichols DE, Nichols CD

Europe PMC2025
PreprintPsilocybin

The selective 5-HT <sub>2A</sub> receptor agonist LPH-5 induces persistent and robust antidepressant-like effects in rodents

Jensen AA, Cecchi CR, Hibicke M +6

Europe PMC2024
ArticlePsilocybin

Preadministration of Lorazepam Reduces Efficacy and Longevity of Antidepressant-Like Effect from a Psychedelic.

Hibicke M, Billac G, Nichols CD

Europe PMC2024
ArticlePsychedelics

If Everything Is Psychedelic, Then Nothing Is: A Response to O'Donnell et al. and Lepow et al.

Nichols DE, Hendricks PS, Nichols CD

Europe PMC2023
ArticleDMT

5-MeO-DMT: An atypical psychedelic with unique pharmacology, phenomenology &amp; risk?

Dourron HM, Nichols CD, Simonsson O +3

Europe PMC2025
ArticlePsychedelics

The Elephant in the Room: Personal Use of Psychedelics Among Psychedelic Researchers.

Hendricks PS, Nichols CD

Europe PMC2023
ArticleKetamine

Psychedelic Commercialization: A Wide-Spanning Overview of the Emerging Psychedelic Industry.

Aday JS, Barnett BS, Grossman D +3

Europe PMC2023
ArticlePsychedelics

Proposed Consensus Statement on Defining Psychedelic Drugs.

Nichols DE, Nichols CD, Hendricks PS

Europe PMC2023
ArticlePsychedelics

Past, Present, and Future of Psychedelics: A &lt;i&gt;Psychedelic Medicine&lt;/i&gt; Roundtable Discussion.

Hendricks PS, Nichols CD, Cunningham KA +3

Europe PMC2023
ArticlePsilocybin

A Single Administration of Psilocybin Persistently Rescues Cognitive Deficits Caused by Adolescent Chronic Restraint Stress Without Long-Term Changes in Synaptic Protein Gene Expression in a Rat Experimental System with Translational Relevance to Depression.

Hibicke M, Kramer HM, Nichols CD

Europe PMC2023
ArticlePsychedelics

Editors' Introduction to &lt;i&gt;Psychedelic Medicine&lt;/i&gt;.

Hendricks PS, Nichols CD

Europe PMC2023
ArticlePsilocybin

Preclinical perspectives on the mechanisms underlying the therapeutic actions of psilocybin in psychiatric disorders.

Wulff AB, Nichols CD, Thompson SM

Europe PMC2023
ArticlePsilocybin

Psychedelic drug abuse potential assessment research for new drug applications and Controlled Substances Act scheduling.

Henningfield JE, Coe MA, Griffiths RR +10

Europe PMC2022
ArticlePsilocybin

Validation of the forced swim test in Drosophila, and its use to demonstrate psilocybin has long-lasting antidepressant-like effects in flies.

Hibicke M, Nichols CD

Europe PMC2022
ArticleLSD

Lysergic acid diethylamide induces increased signalling entropy in rats' prefrontal cortex.

Savino A, Nichols CD

Europe PMC2022
PreprintLSD

LSD induces increased signalling entropy in rats’ prefrontal cortex

Savino A, Nichols CD

Europe PMC2021
ArticlePsychedelics

Structure-Activity Relationship Analysis of Psychedelics in a Rat Model of Asthma Reveals the Anti-Inflammatory Pharmacophore.

Flanagan TW, Billac GB, Landry AN +3

Europe PMC2021
ArticleKetamine

Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression.

Hibicke M, Landry AN, Kramer HM +2

Europe PMC2020
ArticlePsilocybin

Population Survey Data Informing the Therapeutic Potential of Classic and Novel Phenethylamine, Tryptamine, and Lysergamide Psychedelics.

Sexton JD, Nichols CD, Hendricks PS

Europe PMC2019
ArticleLSD

Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers.

Family N, Maillet EL, Williams LTJ +6

Europe PMC2020
ArticlePsilocybin

Microdosing psychedelics: More questions than answers? An overview and suggestions for future research.

Kuypers KP, Ng L, Erritzoe D +6

Europe PMC2019
ArticlePsilocybin

Psychedelic Drugs in Biomedicine.

Kyzar EJ, Nichols CD, Gainetdinov RR +2

Europe PMC2017