Olson DE

Institute for Psychedelics and Neurotherapeutics, University of California, Davis, CA 95616.

45 papers · ORCID

ArticleLSD

Deconstruction of lysergic acid diethylamide.

Basargin AG, Domokos A, Hennessey JJ +17

Europe PMC2026
ArticleLSD

Skeletal editing by iron-catalyzed carbene insertion of trichloromethanes.

DeMuynck BM, Hyland EE, Kim H +6

Europe PMC2026
ArticleMDMA

<i>R</i>-MDDMA is a Safer Analogue of MDMA with Therapeutic Potential.

Vargas MV, Hatzipantelis CJ, Dunlap LE +7

Europe PMC2026
ArticleKetamine

Zalsupindole is a Nondissociative, Nonhallucinogenic Neuroplastogen with Therapeutic Effects Comparable to Ketamine and Psychedelics.

Agrawal R, Gillie D, Mungenast A +6

Europe PMC2025
ArticlePsilocybin

Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspring.

Hatzipantelis CJ, Liu M, Love A +13

Europe PMC2025
ArticleDMT

Indolethylamine <i>N</i>-Methyltransferase Deletion Impacts Mouse Behavior without Disrupting Endogenous Psychedelic Tryptamine Production.

Hatzipantelis CJ, Cameron LP, Liu M +8

Europe PMC2025
ArticleMDMA

Pharmacological Evaluation of Tropane Analogues at the Serotonin Transporter.

Avanes AA, Warren HT, Senthil A +1

Europe PMC2025
ArticlePsychedelics

The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation.

Aarrestad IK, Cameron LP, Fenton EM +35

Europe PMC2025
ArticleLSD

Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT<sub>2A</sub>R Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq.

Sink A, Pottie E, Carter SJ +7

Europe PMC2025
ArticleLSD

Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential.

Tuck JR, Dunlap LE, Khatib YA +27

Europe PMC2025
ArticleIbogaine

Efficient and modular synthesis of ibogaine and related alkaloids.

Iyer RN, Favela D, Domokos A +7

Europe PMC2025
ArticleKetamine

Toward Translatable Biomarkers of Psychedelic-Induced Neuroplasticity.

Olson DE

Europe PMC2025
ArticlePsychedelics

The psychedelic drug DOI reduces heroin motivation by targeting 5-HT2A receptors in a heroin and alcohol co-use model.

Bonilla J, Giannotti G, Kregar NP +3

Europe PMC2024
ArticlePsilocybin

Rapid, biochemical tagging of cellular activity history in vivo.

Zhang R, Anguiano M, Aarrestad IK +5

Europe PMC2024
ArticlePsychedelics

Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer's Disease.

Warren HT, Saeger HN, Tombari RJ +3

Europe PMC2024
ArticlePsilocybin

The Effects of Psychedelics on Neuronal Physiology.

Hatzipantelis CJ, Olson DE

Europe PMC2024
ArticlePsychedelics

Rapid Synthesis of Psychoplastogenic Tropane Alkaloids.

Chow WL, Gonzalez MA, Avanes AA +1

Europe PMC2023
ArticleLSD

Synthetic Strategies toward Lysergic Acid Diethylamide: Ergoline Synthesis via α-Arylation, Borrowing Hydrogen Alkylation, and C-H Insertion.

Tuck JR, Dunlap LE, Olson DE

Europe PMC2023
ArticlePsychedelics

Therapeutic mechanisms of psychedelics and entactogens.

Heifets BD, Olson DE

Europe PMC2024
ArticleIbogaine

Tabernanthalog Reduces Motivation for Heroin and Alcohol in a Polydrug Use Model.

Heinsbroek JA, Giannotti G, Bonilla J +2

Europe PMC2023
ArticlePsychedelics

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.

Vargas MV, Dunlap LE, Dong C +11

Europe PMC2023
ArticleKetamine

Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish (<i>Danio rerio</i>).

Tombari RJ, Mundy PC, Morales KM +3

Europe PMC2023
ArticlePsilocybin

5-HT2ARs Mediate Therapeutic Behavioral Effects of Psychedelic Tryptamines.

Cameron LP, Patel SD, Vargas MV +6

Europe PMC2023
ArticlePsychedelics

Psychedelics and Neural Plasticity: Therapeutic Implications.

Grieco SF, Castrén E, Knudsen GM +5

Europe PMC2022
ArticlePsychedelics

The neural basis of psychedelic action.

Kwan AC, Olson DE, Preller KH +1

Europe PMC2022
ArticlePsychedelics

Biochemical Mechanisms Underlying Psychedelic-Induced Neuroplasticity.

Olson DE

Europe PMC2022
ArticlePsychedelics

The evolution of the psychedelic revolution.

Cameron LP, Olson DE

Europe PMC2022
ArticlePsilocybin

Psychedelic-inspired approaches for treating neurodegenerative disorders.

Saeger HN, Olson DE

Europe PMC2022
ArticlePsilocybin

Psychedelics and Other Psychoplastogens for Treating Mental Illness.

Vargas MV, Meyer R, Avanes AA +2

Europe PMC2021
ArticleIbogaine

Engineering Safer Psychedelics for Treating Addiction.

Peters J, Olson DE

Europe PMC2021
ArticlePsychedelics

An analog of psychedelics restores functional neural circuits disrupted by unpredictable stress.

Lu J, Tjia M, Mullen B +8

Europe PMC2021
ArticlePsychedelics

Psychedelic-inspired drug discovery using an engineered biosensor.

Dong C, Ly C, Dunlap LE +8

Europe PMC2021
ArticlePsychedelics

The Promise of Psychedelic Science.

Olson DE

Europe PMC2021
ArticlePsychedelics

The Subjective Effects of Psychedelics May Not Be Necessary for Their Enduring Therapeutic Effects.

Olson DE

Europe PMC2021
ArticleIbogaine

A non-hallucinogenic psychedelic analogue with therapeutic potential.

Cameron LP, Tombari RJ, Lu J +26

Europe PMC2021
ArticleKetamine

Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth.

Ly C, Greb AC, Vargas MV +4

Europe PMC2021
ArticleDMT

Identification of Psychoplastogenic <i>N</i>,<i>N</i>-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies.

Dunlap LE, Azinfar A, Ly C +9

Europe PMC2020
ArticleLSD

Psychedelic Microdosing: Prevalence and Subjective Effects.

Cameron LP, Nazarian A, Olson DE

Europe PMC2020
ArticleDMT

Chronic, Intermittent Microdoses of the Psychedelic <i>N</i>,<i>N</i>-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents.

Cameron LP, Benson CJ, DeFelice BC +2

Europe PMC2019
ArticleMDMA

Psychoplastogens: A Promising Class of Plasticity-Promoting Neurotherapeutics.

Olson DE

Europe PMC2018
ArticleDMT

Dark Classics in Chemical Neuroscience: N, N-Dimethyltryptamine (DMT).

Cameron LP, Olson DE

Europe PMC2018
ArticleMDMA

Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine.

Dunlap LE, Andrews AM, Olson DE

Europe PMC2018
ArticleMDMA

Psychedelics Promote Structural and Functional Neural Plasticity.

Ly C, Greb AC, Cameron LP +13

Europe PMC2018
ArticleDMT

Reaction of <i>N</i>,<i>N</i>-Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions.

Dunlap LE, Olson DE

Europe PMC2018
ArticleKetamine

Effects of N, N-Dimethyltryptamine on Rat Behaviors Relevant to Anxiety and Depression.

Cameron LP, Benson CJ, Dunlap LE +1

Europe PMC2018