Pottie E

Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent 9000, Belgium.

12 papers · ORCID

ArticlePsychedelics

N‑Benzyl-Tryptamine Derivatives as Serotonin 5‑HT2 Receptor Ligands: Synthesis and Structure-Affinity/Activity Relationships.

Martínez-Afani D, Soares BA, Mella-Raipán J +5

Europe PMC2026

ArticlePsychedelics

The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents.

Nadal-Gratacós N, Puigseslloses P, Guzmán L +20

Europe PMC2026

ArticlePsychedelics

The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects.

Luethi D, Glatfelter GC, Pottie E +12

Europe PMC2026

ArticleDMT

Neuropharmacology of halogenated DMT analogs: psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential.

Puigseslloses P, Nadal-Gratacós N, Fumàs B +11

Europe PMC2026

ArticleLSD

Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT2AR Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq.

Sink A, Pottie E, Carter SJ +7

Europe PMC2025

ArticleLSD

Comparative Pharmacological Effects of Lisuride and Lysergic Acid Diethylamide Revisited.

Glatfelter GC, Pottie E, Partilla JS +2

Europe PMC2024

ArticleLSD

Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists.

Pottie E, Poulie CBM, Simon IA +7

Europe PMC2023

ArticlePsilocybin

Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.

Glatfelter GC, Pottie E, Partilla JS +12

Europe PMC2022

ArticleLSD

Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists.

Poulie CBM, Pottie E, Simon IA +7

Europe PMC2022

ArticleDMT

Enlightening the "Spirit Molecule": Photomodulation of the 5-HT2A Receptor by a Light-Controllable N,N-Dimethyltryptamine Derivative.

Gerwe H, He F, Pottie E +2

Europe PMC2022

ArticleLSD

Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) Positional Isomers.

Pottie E, Kupriyanova OV, Shevyrin VA +1

Europe PMC2021

ArticlePsychedelics

Serotonin 2A Receptor (5-HT2AR) Activation by 25H-NBOMe Positional Isomers: In Vitro Functional Evaluation and Molecular Docking.

Pottie E, Kupriyanova OV, Brandt AL +3

Europe PMC2021

Pottie E

<i>N</i>‑Benzyl-Tryptamine Derivatives as Serotonin 5‑HT<sub>2</sub> Receptor Ligands: Synthesis and Structure-Affinity/Activity Relationships.

The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents.

The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects.

Neuropharmacology of halogenated DMT analogs: psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential.

Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT<sub>2A</sub>R Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq.

Comparative Pharmacological Effects of Lisuride and Lysergic Acid Diethylamide Revisited.

Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT<sub>2A</sub> Receptor Agonists.

Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.

Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT<sub>2A</sub> Receptor Agonists.

Enlightening the "Spirit Molecule": Photomodulation of the 5-HT<sub>2A</sub> Receptor by a Light-Controllable N,N-Dimethyltryptamine Derivative.

Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)-<i>N</i>-(2-fluorobenzyl)ethanamine (25H-NBF) Positional Isomers.

Serotonin 2A Receptor (5-HT<sub>2A</sub>R) Activation by 25H-NBOMe Positional Isomers: <i>In Vitro</i> Functional Evaluation and Molecular Docking.

Pottie E

&lt;i&gt;N&lt;/i&gt;‑Benzyl-Tryptamine Derivatives as Serotonin 5‑HT&lt;sub&gt;2&lt;/sub&gt; Receptor Ligands: Synthesis and Structure-Affinity/Activity Relationships.

The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents.

The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects.

Neuropharmacology of halogenated DMT analogs: psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential.

Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT&lt;sub&gt;2A&lt;/sub&gt;R Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq.

Comparative Pharmacological Effects of Lisuride and Lysergic Acid Diethylamide Revisited.

Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT<sub>2A</sub> Receptor Agonists.

Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.

Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT<sub>2A</sub> Receptor Agonists.

Enlightening the "Spirit Molecule": Photomodulation of the 5-HT<sub>2A</sub> Receptor by a Light-Controllable N,N-Dimethyltryptamine Derivative.

Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)-<i>N</i>-(2-fluorobenzyl)ethanamine (25H-NBF) Positional Isomers.

Serotonin 2A Receptor (5-HT<sub>2A</sub>R) Activation by 25H-NBOMe Positional Isomers: <i>In Vitro</i> Functional Evaluation and Molecular Docking.

<i>N</i>‑Benzyl-Tryptamine Derivatives as Serotonin 5‑HT<sub>2</sub> Receptor Ligands: Synthesis and Structure-Affinity/Activity Relationships.

Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT<sub>2A</sub>R Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq.