Young AH

Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, London SE5 8AB, United Kingdom; Division of Psychiatry, Department of Brain Sciences, Imperial College London, United Kingdom.

48 papers · 3 preprints · ORCID

ArticlePsychedelics

The effect of psychedelics on associative learning: A systematic review.

Caulfield A, Li L, Belessiotis-Richards C +5

Europe PMC2026
ArticleKetamine

Erratum to "Long-term treatment with esketamine nasal spray in patients with treatment resistant depression: Results from the ESCAPE-LTE study" [European Neuropsychopharmacology 107 (2026) 112801].

Reif A, Anıl YA, Bitter I +11

Europe PMC2026
ArticlePsilocybin

Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial.

Rucker JJ, Mantingh T, Kerr-Gaffney J +26

Europe PMC2026
ArticleKetamine

Global perspectives on central nervous system drug innovation: achievements, barriers, and priorities for the next decade.

Uchida H, Gobbi G, Zohar J +7

Europe PMC2026
ArticleKetamine

Clinical guidance on the use of esketamine nasal spray for patients with treatment resistant depression: A European Delphi consensus report.

Young AH, Baune BT, Benatti B +13

Europe PMC2026
ArticleKetamine

Trajectory of response to esketamine nasal spray for treatment resistant depression: Findings from ESCAPE-TRD.

Young AH, Bartova L, Cardoner N +9

Europe PMC2026
ArticleKetamine

Response to: Commentary on "Long-term treatment with esketamine nasal spray in patients with treatment resistant depression: Results from the ESCAPE-LTE study".

Reif A, Anıl Yağcıoğlu AE, Bitter I +11

Europe PMC2026
ArticlePsilocybin

A systematic review of the pharmacokinetics of classical serotonergic psychedelic compounds in healthy adult subjects.

Hampsey E, Martin K, Kalfas M +5

Europe PMC2026
ArticlePsilocybin

Olanzapine for young people with anorexia nervosa: a synopsis of the main results from the OPEN open-label feasibility study.

Filiz ES, Stringer D, Kellermann V +27

Europe PMC2026
ArticleKetamine

Regional Blood Flow Signatures of Opioidergic Modulation of Ketamine in Major Depressive Disorder: A Randomized Crossover Study.

Jelen LA, O'Daly O, Zelaya FO +3

Europe PMC2026
ArticlePsilocybin

The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression: A post hoc path analysis.

Goodwin GM, Aaronson ST, Alvarez O +23

Europe PMC2026
ArticlePsilocybin

Effects of psilocybin on personality, psychiatric symptoms, and values: Exploring mediating effects of the acute psychedelic experience.

Kerr-Gaffney J, Myrtle S, Askari F +4

Europe PMC2026
ArticlePsychedelics

Learning as the unifying mechanism of psychedelic action.

Caulfield A, Young AH, Mehta M

Europe PMC2026
ArticleKetamine

A long, strange trip: Ketamine treatment in psychiatry.

Nutt DJ, Morgan C, Erritzoe D +2

Europe PMC2025
ArticleKetamine

(Es)ketamine as a treatment for depressive episodes with psychotic features: systematic review.

Santos HC, Rodrigues A, Machado T +3

Europe PMC2025
ArticlePsilocybin

Corrigendum to "The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression" [Journal of Affective Disorders, Volume 372 (2025), Pages 523-532].

Goodwin GM, Aaronson ST, Alvarez O +28

Europe PMC2026
ArticleKetamine

Comment on Esketamine Treatment for Depression in Adults: A PRISMA Systematic Review and Meta-Analysis.

Canuso CM, Bossie C, Fu DJ +12

Europe PMC2025
PreprintKetamine

Regional blood flow signatures of opioidergic modulation of ketamine in major depressive disorder: a randomised crossover study

Jelen LA, O’Daly O, Zelaya FO +3

Europe PMC2025
ArticleKetamine

Effect of naltrexone pretreatment on ketamine-induced glutamatergic activity and symptoms of depression: a randomized crossover study.

Jelen LA, Lythgoe DJ, Stone JM +2

Europe PMC2025
PreprintPsychedelics

The effect of psychedelics on associative learning: a systematic review

Caulfield A, Li L, Askari F +3

Europe PMC2025
ArticleKetamine

Urological symptoms following ketamine treatment for psychiatric disorders: A systematic review.

Kerr-Gaffney J, Tröger A, Caulfield A +3

Europe PMC2025
ArticleKetamine

A randomized, double-blind, placebo-controlled, Phase 1 study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of an immediate-release oral ketamine capsule in healthy volunteers.

Qureshi M, Silman D, Gadelrab R +7

Europe PMC2025
ArticleKetamine

Efficacy of esketamine nasal spray over quetiapine extended release over the short and long term: sensitivity analyses of ESCAPE-TRD, a randomised phase IIIb clinical trial - ERRATUM.

Young AH, Llorca PM, Fagiolini A +9

Europe PMC2025
ArticleKetamine

Safety and efficacy with esketamine in treatment-resistant depression: long-term extension study.

Zaki N, Chen LN, Lane R +10

Europe PMC2025
ArticlePsilocybin

Psychedelic-assisted treatment for substance use disorder: A narrative systematic review.

Piper T, Small F, Brown S +5

Europe PMC2025
ArticlePsilocybin

The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.

Goodwin GM, Aaronson ST, Alvarez O +28

Europe PMC2025
ArticleKetamine

Efficacy of esketamine nasal spray over quetiapine extended release over the short and long term: sensitivity analyses of ESCAPE-TRD, a randomised phase IIIb clinical trial.

Young AH, Llorca PM, Fagiolini A +9

Europe PMC2025
ArticlePsilocybin

Is it now time to prepare psychiatry for a psychedelic future?

Nutt D, Crome I, Young AH

Europe PMC2024
ArticleKetamine

Safety and tolerability of esketamine nasal spray versus quetiapine extended release in patients with treatment resistant depression.

McIntyre RS, Bitter I, Buyze J +9

Europe PMC2024
ArticleKetamine

Extended-release ketamine tablets for treatment-resistant depression: a randomized placebo-controlled phase 2 trial.

Glue P, Loo C, Fam J +3

Europe PMC2024
ArticleKetamine

Guidelines for ketamine use in clinical psychiatry practice.

Jelen LA, McShane R, Young AH

Europe PMC2024
ArticleDMT

Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-<i>N,N</i>-dimethyltryptamine benzoate) in healthy participants.

Rucker JJ, Roberts C, Seynaeve M +6

Europe PMC2024
ArticlePsilocybin

Psilocybin for dementia prevention? The potential role of psilocybin to alter mechanisms associated with major depression and neurodegenerative diseases.

Haniff ZR, Bocharova M, Mantingh T +7

Europe PMC2024
ArticleKetamine

Ketamine cystitis following ketamine therapy for treatment-resistant depression - case report.

Chang M, Juruena MF, Young AH

Europe PMC2024
ArticleAyahuasca

Corrigendum: Ceremonial ayahuasca in amazonian retreats-mental health and epigenetic outcomes from a six-month naturalistic study.

Ruffell SGD, Netzband N, Tsang W +8

Europe PMC2023
ArticleKetamine

Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions.

McIntyre RS, Alsuwaidan M, Baune BT +24

Europe PMC2023
ArticlePsilocybin

Psychedelics for treatment resistant depression: are they game changers?

Kalfas M, Taylor RH, Tsapekos D +1

Europe PMC2023
ArticlePsilocybin

Psilocybin therapy for treatment resistant depression: prediction of clinical outcome by natural language processing.

Dougherty RF, Clarke P, Atli M +10

Europe PMC2025
ArticlePsychedelics

Science, safety and education: Informing the psychedelic treatment of psychiatric disorders.

Young AH

Europe PMC2023
ArticlePsilocybin

Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020.

Kopra EI, Ferris JA, Winstock AR +3

Europe PMC2023
ArticleKetamine

Early Clinical Experiences of Esketamine Nasal Spray in the UK in Adults with Treatment-Resistant Major Depressive Disorder: Advisory Panel Recommendations.

Young AH, Abdelghani M, Juruena MF +2

Europe PMC2023
PreprintPsilocybin

Psilocybin Therapy for Treatment Resistant Depression: Prediction of Clinical Outcome by Natural Language Processing

Dougherty RF, Clarke P, Alti M +10

Europe PMC2022
ArticleLSD

Adverse experiences resulting in emergency medical treatment seeking following the use of lysergic acid diethylamide (LSD).

Kopra EI, Ferris JA, Rucker JJ +4

Europe PMC2022
ArticlePsilocybin

Adverse experiences resulting in emergency medical treatment seeking following the use of magic mushrooms.

Kopra EI, Ferris JA, Winstock AR +2

Europe PMC2022
ArticlePsilocybin

The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation.

Rucker JJ, Marwood L, Ajantaival RJ +12

Europe PMC2022
ArticleKetamine

Cardiovascular Effects of Combining Subcutaneous or Intravenous Esketamine and the MAO Inhibitor Tranylcypromine for the Treatment of Depression: A Retrospective Cohort Study.

Ludwig VM, Sauer C, Young AH +4

Europe PMC2021
ArticleAyahuasca

Ceremonial Ayahuasca in Amazonian Retreats-Mental Health and Epigenetic Outcomes From a Six-Month Naturalistic Study.

Ruffell SGD, Netzband N, Tsang W +7

Europe PMC2021
ArticlePsilocybin

Psilocybin: From Serendipity to Credibility?

Rucker JJ, Young AH

Europe PMC2021
ArticleAyahuasca

The pharmacological interaction of compounds in ayahuasca: a systematic review.

Ruffell S, Netzband N, Bird C +2

Europe PMC2020
ArticlePsilocybin

Psychedelic treatment of functional neurological disorder: a systematic review.

Butler M, Seynaeve M, Nicholson TR +5

Europe PMC2020
ArticlePsilocybin

Psychedelics in the treatment of unipolar mood disorders: a systematic review.

Rucker JJ, Jelen LA, Flynn S +2

Europe PMC2016