Zhang Y

Safety, efficacy, and opioid-sparing effects of ketamine for analgesia in traumatic chest injury and rib fractures: a systematic review and meta-analysis

Zhang K, Zheng J, Zhang Y +3

Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Response to Letter].

Qin X, Jiang H, Xie Y +3

Ketamine metabolite HNK ameliorates anhedonia symptom in Alzheimer's disease mice.

Yang S, Guo B, Deng D +2

5-HT2A receptor activation is dispensable for psilocybin-induced fear extinction and neuroplasticity in mice.

Du Y, Zhao X, Chen Q +4

PreprintKetamine

In Vitro Ketamine Attenuates Immune Sensitization in Major Depressive Disorder in a Concentration-Dependent Manner

Zhang Y, Zhuang X, Niu M +7

Esketamine Attenuates Postoperative Neurocognitive Disorder in Aged Mice: Associations with Bioenergetic Remodeling in Hippocampal CD11b-Enriched Cell Fractions and Glycolysis-Related Signaling.

Liu D, Li G, Huang H +3

Efficacy and Safety of Psychedelic Microdosing on Psychological Outcomes in Healthy Adults: A Systematic Review and Meta-analysis.

Meshkat S, Leung M, Meshkat S +13

Network Pharmacology Reveals the Potential Mechanism of Ketamine in Improving Cognitive Impairment in Patients With Depression.

Yang L, Zhang Q, Zhang Y +4

The Effect of Esketamine Combined with Pulsed Radiofrequency on Neuropathic Pain in Herpes Zoster Patients: A Randomised Clinical Trial.

Wang D, Gai Q, Zhang Y +3

CB1R-dependent mitochondrial biogenesis may contribute to the antidepressant effects of esketamine in a chronic variable stress male mouse model.

Zhao W, Zhao X, Zhang Y +7

A scoping review: ketamine or esketamine when used to assist psychotherapy or in combination with psychotherapy for the management of depression in adults.

Swainson J, Grewal P, Polard S +9

The median effective dose (ED50) of remimazolam combined with esketamine for conscious sedation in patients with dental anxiety undergoing outpatient dental surgery: a prospective, dose-finding study.

Che M, Kang C, Zhou C +7

Investigating the impact of serotonergic psychedelic drugs, MDMA and ketamine on social cognition in psychiatric disorders: A scoping review.

Smith SA, Mohammad H, Lee LHN +13

Comparative Efficacy of Dexmedetomidine and Esketamine on Postoperative Sleep Disturbances and Analgesia: A Systematic Review and Network Meta-Analysis.

Jiang T, Zhao R, Zhang Y +10

DESI-MSI-Based Multi-Organ Distribution Mapping of Psilocin in Zebrafish.

Dong M, Zhang Y, Cao M +4

Integrated micro-solid-phase extraction with miniature mass spectrometry for on-site detection of illicit drugs in human hair.

Zhang Y, Zhang J, Wu J +10

Increasing dose of esketamine for supplemental analgesia after complex spinal fusion surgery: a randomized and double-blind trial.

Guo ZM, Cui F, Zhang Y +2

A Study on the ED90 of Esketamine Combined with Ropivacaine for Early Epidural Analgesia During the First Stage of Labor in Nulliparous Women: A Randomized, Sequential Dose-Finding Trial.

Lin X, Tu Y, Qiu P +3

Ketamine and esketamine for the prevention of postpartum depression: A systematic review and network meta-analysis, with an integrated evidence synthesis.

Lunsky I, Gutierrez G, Wang X +8

Pharmacological sedation strategies for therapeutic gastrointestinal endoscopy: a systematic review and network meta-analysis of randomised controlled trials.

Jiang H, Xie Y, Qin X +4

Effect of Esketamine on Postoperative Pain in Children Undergoing Plasma Tonsillectomy: A Double-Blind, Randomized Controlled Trial.

Lu Q, Zhang Y, Duan J +1

Clinical applications of esketamine: Current status and future perspectives.

Li H, Deng J, Liu T +1

Evaluation of optimal dosage combinations of oral midazolam and esketamine for pediatric preoperative sedation: A randomized, double-blind clinical trial.

Xiong H, Xu Y, Liu J +8

Commentary on "Long-term treatment with esketamine nasal spray in patients with treatment resistant depression: Results from the ESCAPE-LTE study".

Zhang Y, Xue J, Leng J

Esketamine Alleviates Postoperative Cognitive Dysfunction via Rock2/Add1 Signaling Pathway in Aged Mice.

Xu C, Zhang Y, Liu Y +7

Effective doses of esketamine oral or esketamine intranasal for the prevention of preoperative anxiety in pediatric patients: A randomized double-blind dose-finding trial.

Xiong H, Xu Y, Liu J +8

Magnitude of response in treatment and control groups within psychedelic trials for psychiatric disorders: A meta-analysis.

Meshkat S, Lin Q, Sousa-Ho R +15

Comparative analysis of esketamine versus remimazolam in adult and pediatric surgical patients: a multimodal monitoring evaluation.

Fang H, Zhang Y, Yu Q +1

Remifentanil-esketamine-based General Anesthesia Strategy for Microelectrode-guided Deep-brain Stimulation for Parkinson Disease.

Huang D, Luo H, Shu H +6

ED95 of Ciprofol Combined with Esketamine or Sufentanil in Elderly Patients Undergoing Endoscopic Submucosal Dissection: A Dose-Finding and Randomized Controlled Trial.

Qin X, Jiang H, Xie Y +3

Esketamine attenuates bone cancer pain by suppressing MAPK signaling and glial activation in the spinal dorsal horn of rats.

Cheng L, Wang D, Zhang Z +9

Promotion of lung cancer growth via glutamate ionotropic receptor N-methyl-D-aspartate-type subunit 2D (GRIN2D).

Lv Y, Bu X, Du Z +5

A retrospective report of a ketamine-augmented, transdiagnostic psychiatric outpatient psychotherapy program.

Stefanuk I, Chivers-Wilson K, Jetly R +4

Toward a definition of treatment-resistant posttraumatic stress disorder: A systematic review.

Al-Shamali HF, Meshkat S, Janssen-Aguilar R +12

Esketamine combined with hydromorphone versus hydromorphone for post-operative patient-controlled intravenous analgesia in children: a randomized controlled trial.

Li Y, Wang L, Liu K +4

Intravenous Esketamine Versus Erector Spinae Plane Block for Postoperative Recovery Quality Following Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Non-Inferiority Trial.

Liu Z, Zhao H, Ning Y +6

Mixed toxin profiles in two new and one known species of Inocybe (Inocybaceae) from northern China

Liang J, Chen X, Liu T +7

Esketamine Alleviates Neuropathic Pain and Inflammation via miR-153-3p/AKT3 in CCI Rats.

Zhu X, Zhang Y

Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Response to Letter]

Qin X, Jiang H, Xie Y +3

Effect of Esketamine Combined with Lidocaine on Opioid Requirements in the Elderly Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized, Double-Blind, Controlled Trial.

Xie JX, Wang X, Li Y +5

Effects of Intravenous Subanesthetic-Dose Esketamine on Early Postoperative Pain in Elderly Patients Undergoing Thoracoscopic Lung Surgery: A Randomized Double-Blind Controlled Trial.

Zhao H, Liu Z, Zhang Y +6

Intestinal γδ T17-IL-17A signaling disrupts hippocampal mitophagy in stress-induced depression and is restored by arketamine.

Han M, Xie B, Yu Y +15

Effects of Subanesthetic Esketamine on Postoperative Sleep Quality Through EEG Analysis in Breast Cancer Patients: A Randomized Clinical Trial.

Zhan Y, Zhang Y, Liu Z +4

Opioid-free anesthesia with esketamine combined with interpectoral plane block and pectoralis-serratus plane blocks in radical mastectomy: a randomized controlled trial.

Ding W, Deng Y, Sun N +6

Novel and emerging anesthetic drugs for the treatments of major depression: a comprehensive review of efficacy, mechanism, and outlook.

Li C, Wang Z, Ye X +11

Ascorbic acid enhances antidepressant-like efficacy of esketamine: Hippocampal TARP-γ8-containing AMPA receptors mediate synaptic modulation.

Ke Z, Zhang Y, Jiang X +6

Efficacy and safety of esketamine on major depression, postpartum depression and perioperative depression: a systematic review and meta-analysis.

Huang C, Hu L, Liu W +7

Effect of esketamine as an adjuvant of ropivacaine on the efficacy of supraclavicular brachial plexus block in radius fracture surgery: a randomized controlled trial.

Liu J, Zhang Y, Zhang R +5

Effect of intraoperative low-dose esketamine on postoperative quality of recovery in patients undergoing laparotomy for gynecologic malignancy: a randomized controlled trial.

Geng ZY, Zhang Y, Bi H +3

Safety and efficacy of esketamine combined with propofol or ciprofol sedation for electroconvulsive therapy in patients with major depressive disorder: protocol for a randomized, double-blind, controlled trial with factorial design.

Zhang Y, Su DZ, Chen R +4

A comparative study of dexmedetomidine combined with esketamine and sufentanil for sedation and analgesia in patients undergoing microwave ablation of lung tumors: A prospective single-center randomized double-blind clinical trial.

Li Y, Li Y, Zhang Y +6

The Impact of Esketamine on Depression: Targeting Oxidative Stress and Neuronal Apoptosis Through BDNF/TrkB/PI3K/AKT Pathway Activation.

Zhang Y, Cai Q, Wang L +1

Intraoperative low-dose esketamine on postoperative quality of recovery in patients undergoing open gynecologic surgery: a double-blinded, parallel-group, placebo- controlled trial.

Geng ZY, Zhang Y, Yan X +4

Effect of Perioperative Subanesthetic Dose of Esketamine on Postoperative Recovery Quality in Patients Undergoing Laparoscopic Gastrointestinal Surgery: A Randomised, Double-Blind, Controlled Trial.

Zhang Y, Li S, Wu C +3

ArticleLSD

[Establishment and application of a high-throughput screening method for drugs targeting the 5-hydroxytryptamine 2A receptor based on cellular calcium flux signals].

Zhang B, Shi J, Zhang Y +4

Interventional Psychiatry and Emerging Treatments for Posttraumatic Stress Disorder (PTSD): A Systematic Review.

Janssen-Aguilar R, Meshkat S, Al-Shamali HF +14

Evolving Psychotherapeutic Approaches for PTSD: Beyond the Fear-Based Model.

Burback L, Winkler O, Jetly R +4

Developmental toxicity and transcriptome analysis of zebrafish (Danio rerio) embryos exposed to anesthetic esketamine.

Wang J, Zhang Y, Liu Y +5

Effects of Binaural Beat Music and Esketamine for ECT in the Treatment of Major Depressive Disorder: A Randomized Controlled Trial Protocol.

Zhang Y, Ke Z, Luo J +4

Opioid-Free Anesthesia Improved the Quality of Recovery After Thyroidectomy Through Pre-Emptive and Preventive Analgesia: A Randomized Controlled Trial.

Zhang Y, Xian X, Wang F +5

The molecular mechanisms through which psilocybin prevents suicide: evidence from network pharmacology and molecular docking analyses.

Zhang Y, Yang L, Zhang Q +3

Effects of sub-anesthetic doses of esketamine on postoperative sleep disturbance and pain in patients undergoing lumbar interbody fusion-A randomized, double-blind, placebo-controlled, two-center trial.

Chen Z, Gao Y, Gao C +9

Effects of Remimazolam Tosilate Combined with Esketamine on Anesthetic Efficacy and Psychiatric Symptoms in Patients Undergoing Ambulatory Surgery: A Randomized Controlled Study.

Yu X, Xu X, Wang J +2

Effect of esketamine on postinduction hypotension in elderly patients undergoing elective noncardiac surgery: a secondary analysis of a randomized clinical trial.

Zhang Y, Zhou Q, Chen R +4

ArticleLSD

Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development.

Courtney Y, Head JP, Dani N +7

Psilocybin mitigates behavioral despair and cognitive impairment in treatment-resistant depression model using wistar kyoto rats.

Wang Z, Robbins B, Zhuang R +4

Effects of esketamine-based opioid-sparing anesthesia protocol in Bama miniature pigs undergoing robot-assisted nephrectomy.

Zhou M, Li W, Sun J +5

PreprintPsilocybin

Psilocybin Mitigates Behavioral Despair and Cognitive Impairment in Treatment-resistant Depression Model using Wistar Kyoto Rats

Wang Z, Robbins B, Zhuang R +4

Therapeutic Effects of Low-Dose Psilocybin in Depression and Other Mental Disorders: A Systematic Review.

Meshkat S, Fang H, Sousa-Ho R +11

Advances in the study of NMDA receptors in depression pathogenesis and the antidepressant efficacy of their antagonists.

Chen M, Jin J, Bi H +4

Efficacy and safety of psilocybin for the treatment of substance use disorders: A systematic review.

Meshkat S, Malik G, Zeifman RJ +12

Ascorbic Acid and Esketamine for Mental Disorders in Women with Miscarriage: A Randomized Controlled Double-Blind Trial Protocol.

Ke Z, Zhang Y, Cai B +4

Inhibition of autophagy by esketamine attenuates hypoxia/reoxygenation injury in cardiomyocytes via inhibition of Ca2+/CaMKKβ/AMPK/mTOR pathway by down-regulation of transient receptor potential vanilloid 1 expression.

Zhang Y, Lu QM, Hu HC +2

Association between ketamine use and mortality in critically ill patients receiving mechanical ventilation: Analysis of the MIMIC-IV database.

Yang Y, Luo H, Zhang Y +2

Pharmacokinetics of Psilocybin: A Systematic Review.

Meshkat S, Al-Shamali H, Perivolaris A +13

Psychedelics and Suicide-Related Outcomes: A Systematic Review.

Meshkat S, Malik T, Zeifman R +13

Efficacy of intranasal dexmedetomidine-esketamine sedation for pediatric acceptance of facemask: single-center, double-blind, randomized, controlled trial.

Zhang K, Zhang G, Zhang Y +4

Effects of epidural esketamine versus sufentanil on labor analgesia and postpartum depression: a retrospective cohort study.

Li K, Chai Z, Deng C +5

Esketamine alleviates LPS-induced depression-like behavior by activating Nrf2-mediated anti-inflammatory response in adolescent mice.

Ma X, Xue S, Ma H +8

Effects of esketamine on postoperative pain and inflammatory factors in children undergoing tonsillectomy and adenoidectomy.

Zhu Y, Wang X, Wang L +1

The Effects of Opioid-Free Anesthesia with Dexmedetomidine and Esketamine on Postoperative Anesthetic-Related Complications for Hip Surgery in the Elderly.

Ye Q, Hu Y, Xing Q +2

Comparative Analysis of Hemodynamic Effects of Remimazolam and Propofol Combined with Esketamine in Colonoscopic Procedures in the Elderly.

Deng BR, Zhang Y, Xie ZF +7

Rapid on-site detection of illicit drugs in urine using C18 pipette-tip based solid-phase extraction coupled with a miniaturized mass spectrometer.

Wu J, Zhang Y, Zhang M +10

Impact of psilocybin on cognitive function: A systematic review.

Meshkat S, Tello-Gerez TJ, Gholaminezhad F +11

Accurate Machine Learning-based Monitoring of Anesthesia Depth with EEG Recording.

Tu Z, Zhang Y, Lv X +9

The CB2-PKC pathway is involved in esketamine-induced anti-inflammation in BV-2 microglial cells exposed to lipopolysaccharides.

Wang Y, Cao M, Zhang Y +3

Diurnal variation of postoperative delirium in elderly patients undergoing esketamine anesthesia for elective noncardiac surgery: a randomized clinical trial.

Zhang Y, Chen R, Tang S +8

Investigating the impact of psychedelic drugs on social cognition defects: A scoping review protocol.

Smith SA, Smith S, Dennett L +1

A scientometric analysis of research on the role of NMDA receptor in the treatment of depression.

Chen X, Wang X, Li C +3

Effects of esketamine and fluoxetine on depression-like behaviors in chronic variable stress: a role of plasma inflammatory factors.

Chen H, Zhao X, Ma X +6

Alterations in brain network connectivity and subjective experience induced by psychedelics: a scoping review.

Yu Z, Burback L, Winkler O +11

Esketamine alleviates hypoxia/reoxygenation injury of cardiomyocytes by regulating TRPV1 expression and inhibiting intracellular Ca2+ concentration.

Zhang Y, Lu Q, Hu H +2

The efficacy of nasal administration of esketamine in patients having moderate-to-severe pain after preoperative CT-guided needle localization: a randomized, double-blind, placebo-controlled trial.

Xu J, Jian J, Zhang Y +2

Effects of esketamine on postoperative negative emotions and early cognitive disorders in patients undergoing non-cardiac thoracic surgery: A randomized controlled trial.

Luo T, Deng Z, Ren Q +3

Efficacy of epidural esketamine on postoperative sleep quality after laparoscopic and robotic lower abdominal surgeries: a study protocol for randomised, double-blind, controlled trial.

Yang Y, Zhang Y, Zhou G +3

ArticleLSD

Repeated microdoses of LSD do not alter anxiety or boldness in zebrafish.

Hagen EV, Schalomon M, Zhang Y +1

A systematic review and meta-analysis of the efficacy of ketamine and esketamine on suicidal ideation in treatment-resistant depression.

Wang YT, Wang XL, Lei L +5

Apoptotic mechanism of development inhibition in zebrafish induced by esketamine.

Yuan W, Xiao Y, Zhang Y +4

Effect of esketamine pretreatment on acute sepsis-associated encephalopathy.

Wang CM, Zhang Y, Yang YS +2

Esketamine mitigates cognitive impairment following exposure to LPS by modulating the intestinal flora/subdiaphragmatic vagus nerve/spleen axis.

Wu Y, Zhang Y, Xie B +3

Median effective dose (ED50) of esketamine combined with propofol for children to inhibit response of gastroscope insertion.

Su M, Zhu Y, Liu S +5

Comparison of remifentanil and esketamine in combination with propofol for patient sedation during fiberoptic bronchoscopy.

Nie J, Chen W, Jia Y +2

Mini-dose esketamine-dexmedetomidine combination to supplement analgesia for patients after scoliosis correction surgery: a double-blind randomised trial.

Zhang Y, Cui F, Ma JH +1

Esketamine is neuroprotective against traumatic brain injury through its modulation of autophagy and oxidative stress via AMPK/mTOR-dependent TFEB nuclear translocation.

Tang Y, Liu Y, Zhou H +4

Risk of esketamine anesthesia on the emergence delirium in preschool children after minor surgery: a prospective observational clinical study.

Chen S, Yang JJ, Zhang Y +6

Effect of esketamine on opioid consumption and postoperative pain in thyroidectomy: A randomized controlled trial.

Wang P, Song M, Wang X +2

PreprintKetamine

Effects of esketamine on postoperative pain and inflammatory factors in children undergoing tonsillectomy and adenoidectomy

zhu y, Wang X, Yuan M +2