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Clinical trial

Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery

Centre Hospitalier Universitaire, AmiensRecruitingPhase 3Started Sep 22, 2026182 enrolledFranceNCT07414706

Abstract

This randomized controlled trial evaluates whether perioperative intravenous lidocaine infusion, combined with port-site ropivacaine infiltration, improves postoperative recovery after laparoscopic abdominal surgery. Participants will be assigned 1:1 to receive either intravenous lidocaine during surgery plus ropivacaine infiltration at surgical closure, or ropivacaine infiltration alone. The primary endpoint is postoperative quality of recovery measured by the QoR-15 questionnaire. Secondary endpoints include postoperative pain and opioid consumption, as well as plasma lidocaine and ropivacaine concentrations to assess systemic exposure and safety.

Topics & conditions

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Pain

Keywords

Intravenous lidocainelaparoscopic surgerypost operative recoverylocal anaesthetic systemic toxicityIntravenous LidocaineLaparoscopic SurgeryPost Operative RecoveryLocal Anaesthetic Systemic Toxicity

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