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Clinical trial

Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia

Federal University of São PauloCompletedPhase 3Started Sep 1, 201060 enrolledBrazilNCT01301079

Abstract

The aim of this study was to determine if the addition of ketamine reduces remifentanil-induced hyperalgesia, improves its analgesic effect, inhibits IL(interleukin)-6 and IL-8 (inflammatory cytokines), and stimulates IL-10 (an anti-inflammatory cytokine).

Topics & conditions

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KetaminePain

Keywords

RemifentanilHyperalgesiaVon Frey's filamentAlgometerInterleukinesOpioid-induced hyperalgesiaHyperalgesiaInflammatory Response

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