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Clinical trial

Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users

Janssen Research & Development, LLCCompletedPhase 1Started Mar 25, 201655 enrolledUnited StatesNCT02682225

Abstract

The primary objective of this study is to evaluate the abuse potential of intranasal esketamine (112 milligram and 84 mg) compared to racemic intravenous ketamine (0.5 mg/kg) in nondependent, recreational polydrug users of perception-altering drugs.

Topics & conditions

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Ketamine

Keywords

EsketaminePlaceboRacemic ketaminePharmacokineticsDrug Abuse

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