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Clinical trial

Ketamine and Levetiracetam as Second-line Antiseizure Medication for Status Epilepticus in Children

Sohag UniversityRecruitingPhase 2Started Jul 2, 2025124 enrolledEgyptNCT07046611

Abstract

About 40% of children with generalized convulsive status epilepticus (GCSE) are not terminated by first-line benzodiazepines (BDZs), and approximately 50% of BDZ-refractory GCSE are not controlled by second-line antiseizure medications. This study investigates the efficacy of ketamine-levetiracetam combination vs. levetiracetam alone for treating children with BDZ-refractory GCSE.

Topics & conditions

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Ketamine

Keywords

Generalized Convulsive Status Epilepticus

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