Clinical trial

Influence of Bupropion on the Effects of MDMA

University Hospital, Basel, SwitzerlandCompletedPhase 1Started Jan 1, 201316 enrolledSwitzerlandNCT01771874

Abstract

The purpose of this study is to determinate the effect of a pre-treatment with bupropion, a dopamine and norepinephrine transporter inhibitor, on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The study will provide further understanding of the dopaminergic regulation of mood.

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

MDMAAddiction

Keywords

pharmacokineticspharmacodynamicsemotionsMechanism of action of MDMAInteraction studyEffect of MDMA and bupropion on emotionsHealthySubstance-related Disorders

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