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Clinical trial

Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department

Tel-Aviv Sourasky Medical CenterCompletedPhase 4Started Nov 1, 200860 enrolledIsraelNCT00784498

Abstract

The use of procedural sedation and analgesia (PSA) to accomplish painful procedures in the emergency department (ED) has become a standard of practice over the last decade. Substantial variance exists regarding usage of medication for PSA, and many anesthetic agents have been proposed for this use. To our knowledge no head to head study compared the clinical effectiveness, safety profile and amnestic properties of midazolam/ketamine vs. propofol regimens for PSA in the adult ED setting. This prospective randomized trail can will help to evaluate the effectiveness and safety profile of Midazolam/katamine regimen for ED PSA in adults and will contribute to the discussion regarding propofol roll in the ED.

Topics & conditions

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Ketamine

Keywords

Procedural sedation and analgesiaEmergency Departmentpropofol versus ketamine and midazolampainful orthopedic manipulationsProcedural Sedation

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