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Protocol and Pilot Data for the PEAK Study (Propofol-Enhanced Blinding of Ketamine vs Placebo in Chronic Pain and Depression)

OSFSep 17, 2025

Abstract

This repository contains de-identified materials from the PEAK study, a randomized, double-blind, placebo-controlled trial designed to evaluate the analgesic and antidepressant effects of ketamine when masked by propofol sedation. The published peer-reviewed manuscript of the protocol and pilot results can be accessed at DOI: 10.1080/17581869.2026.2658080

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

KetamineDepressionPain

Keywords

BlindingChronic PainExpectanciesPlaceboPropofolSedation

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