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Clinical trial

Comparison of the Effects of Dexmedetomidine and Ketamine Infusion on the Inflammatory Response in Liver Resection

Ataturk UniversityCompletedStarted Jun 30, 202245 enrolledTurkey (Türkiye)NCT06219928

Abstract

Resection is being performed with increasing frequency in the treatment of surgical diseases of the liver. Ischemia-reperfusion injury is a major cause of liver injury occurring during surgical procedures, including hepatic resection and liver transplantation. Dexmedetomidine and ketamine, which are frequently used in anesthesia practice, also have strong anti-inflammatory capacity. The primary aim of this study is to investigate the effect of iv low-dose ketamine and dexmedetomidine infusion on inflammation in liver resection surgery, and the secondary aim is to determine its effect on pain scores.

Topics & conditions

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KetaminePain

Keywords

Liver resectiondexmedetomidineinflammationInflammationAnalgesia

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