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Clinical trial

Intra-op Lidocaine and Ketamine Effect on Postoperative Bowel Function

University of SaskatchewanTerminatedStarted Sep 1, 200560 enrolledCanadaNCT00229567

Abstract

Bowel function after bowel surgery is delayed (postoperative ileus)by both opiates and the surgery itself. We hypothesized that decreasing opiate use by other analgesics will speed the return of bowel function after surgery. Lidocaine and Ketamine are drugs that appear to be synergistic and do not slow peristalsis. This study is a Randomised Controlled Trial of Lidocaine Infusion Plus Ketamine Injection versus Placebo to to determine whether they will decrease opiate use and then whether decreased opiate use will speed the return of bowel function.

Topics & conditions

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KetaminePalliative care

Keywords

lidocainepostoperative ileusrandomized controlled trialacute postoperative painColorectal Cancer

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