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Clinical trial

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

University of SaskatchewanCompletedPhase 3Started Oct 15, 201750 enrolledCanadaNCT02987985

Abstract

The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, lidocaine, and gabapentin can help reduce postoperative respiratory depression in the post-anesthesia care unit and ward in children with sleep-disordered breathing undergoing tonsillectomy when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative respiratory depression in children with sleep-disordered breathing.

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

KetamineDepressionAddiction

Keywords

Opioid-sparingOpioid-freeAnesthesiaGeneral AnesthesiaAnalgesics, OpioidPostoperative ComplicationsPathologic ProcessesPhysiologic Effects of DrugsNarcoticsAnalgesicsSleep Disordered BreathingObstructive Sleep Apnea of ChildTonsillectomyRespiratory DepressionDexmedetomidine

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