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Psilocybin-Assisted Therapy for Trauma-Related Disorders: A Scoping Review of a Depression-Dominated Evidence Base with Implications for Intimate Partner Violence-Related PTSD

OSFOct 6, 2025

Abstract

This scoping review examines the emerging evidence for psilocybin-assisted therapy (PAP) in treating trauma-related disorders such as posttraumatic stress disorder (PTSD), depression, and persistent post-concussion symptoms (PPCS), with specific implications for intimate partner violence (IPV)-related brain injury and PTSD. Guided by PRISMA-ScR methodology, we systematically searched Medline, Embase, CINAHL, PsycINFO, and grey literature from 2015–2025 to map existing research, identify gaps, and inform the design of future clinical trials of PaT for IPV survivors.

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PsilocybinDepressionPTSD

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