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Clinical trial

The Neurobiological Effect of 5-HT2AR Modulation

Gitte Moos KnudsenRecruitingPhase 1Started Mar 3, 2017200 enrolledDenmarkNCT03289949

Abstract

The investigators wish to investigate neurobiological effects of serotonin 2A receptor modulation in healthy volunteers, contrasting effects of an agonist (psilocybin) and an antagonist (ketanserin). Magnetic resonance imaging (MRI) and positron emission tomography (PET) will be used as neuroimaging tools.

Topics & conditions

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Psilocybin

Keywords

Basic Science
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Publications from this trial

ArticlePsilocybin

Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headache.

Brendstrup-Brix K, Ozenne B, Fisher PM +10

Europe PMC2026
ArticlePsilocybin

Psilocybin's effect on human brain synaptic plasticity.

Johansen A, Plavén-Sigray P, Madsen MK +14

Europe PMC2026

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Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain.

Spain A, Howarth C, Khrapitchev AA +3

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ArticlePsilocybin

Australia to prescribe MDMA and psilocybin for PTSD and depression in world first.

Haridy R

Europe PMC2023