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A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Supernus Pharmaceuticals, Inc.CompletedPhase 1Started Nov 12, 201819 enrolledUnited StatesNCT03770780

Abstract

This study is a phase 1, double-blind, placebo-controlled crossover study of SAGE-718 using a ketamine challenge, to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic response using magnetic resonance imaging in healthy subjects

Topics & conditions

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Ketamine

Keywords

Healthy Volunteer

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