Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial

Abstract

This protocol describes a feasibility trial that will evaluate the feasibility of conducting a full-scale phase 3 trial testing the hypothesis that a postoperative sustained, low-dose ketamine infusion can prevent postoperative depressive symptoms when administered to a targeted population of neurosurgical patients with a history of depression.

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