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Preregistration

Psilocybin and Irritable Bowel Syndrome: A Scoping Review of the Existing Evidence

OSFApr 27, 2026

Abstract

This scoping review aims to map and summarize the existing evidence on the use of psilocybin in individuals with Irritable Bowel Syndrome (IBS) or related functional gastrointestinal disorders. It will identify what is currently known, highlight gaps in the literature, and outline directions for future research.

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Psilocybin

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