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Peer-reviewed article

Chemical Design and Pharmacokinetics Enable Precision Psychedelic Therapeutics.

Renner ACiD, Kargbo RBiD

ACS medicinal chemistry lettersJan 12, 2026United States0 citationsDOI: 10.1021/acsmedchemlett.5c00780

Abstract

Recent psychedelic patent activity highlights a strategic shift from experiential framing toward chemically and pharmacokinetically precise neurotherapeutics. Four recent patent applications collectively span solid-state control of psilocybin, exposure-shaped intramuscular and infusion-based dosing, and chemically diversified monoaminergic scaffolds with defined transporter and receptor pharmacology. Together, these disclosures outline a platform-level evolution toward reproducible, mechanism-informed psychedelic medicines.

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Psilocybin

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