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Clinical trial

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Yale UniversityRecruitingPhase 2Started Apr 3, 202330 enrolledUnited StatesNCT05786066

Abstract

The purpose of this study is to test the hypothesis that the anti-depressant and anti-suicidal effects of the N-methyl-D-aspartate receptor (NMDAR) antagonist Ketamine is critically dependent on stimulation of Alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid receptors (AMPAR).

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

KetamineDepressionPTSD

Keywords

SuicideDepressive DisorderMajor Depressive DisorderBipolar DisorderPost Traumatic Stress DisorderSuicidal Ideation

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