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Clinical trial

The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery

Ataturk UniversityCompletedStarted Dec 30, 202190 enrolledTurkey (Türkiye)NCT05950555

Abstract

The primary aim of this study was to compare the effects of dexmedetomidine and ketamine, which are administered intravenously during surgery, on the levels of malondialdehyde, an antioxidant, anti-inflammatory enzyme, heme oxygenase-1 enzyme levels and C-reactive protein levels in patients who underwent lower extremity surgery under combined spinal epidural anesthesia.

Topics & conditions

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Ketamine

Keywords

DexmedetomidineOxidative StressAntioxidantMalondialdehydeHeme OxygenaseC-Reactive Protein

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