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Clinical trial

Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery

Ain Shams UniversityRecruitingStarted Jun 1, 202530 enrolledEgyptNCT06995690

Abstract

This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes following spinal anesthesia.

Topics & conditions

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Ketamine

Keywords

Sub-anesthetic doseHypotension preventionNeuraxial anesthesiaHemodynamic stabilityregional anesthesiaASA I-IIDouble-blind randomized trialBlood pressure monitoringEphedrine usePost-spinal HypotensionOrthopedic SurgerySpinal Aneshtesia

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