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Clinical trial

Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation

Brown UniversityRecruitingPhase 1Started Nov 1, 202624 enrolledUnited StatesNCT07818564

Abstract

The primary aim of this phase I mechanistic pilot study is to evaluate the effects of psilocybin on aspects of cognition in healthy adult volunteers. Up to 24 participants will receive a single dose of either psilocybin or inert placebo, and they will be asked to complete several computer-based behavioral tasks measuring features of learning, belief updating, and abstraction. Participants will also complete measures of subjective experience and expectancy, as well as semi-structured interviews at follow up, to assess whether experience correlates with behavior. This is a Voluntary Submission.

Topics & conditions

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Psilocybin

Keywords

psychedeliccognitionlearninghealthy volunteersPhase I

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