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Clinical trial

Pharmacokinetics of Antiepileptics in Patients on CRRT

University of Maryland, BaltimoreCompletedStarted Nov 20, 201718 enrolledUnited StatesNCT03632915

Abstract

The purpose of the study is to measure levels of any of the following AEDs (levetiracetam, phenobarbital, phenytoin, ketamine, valproic acid, lacosamide) in blood and effluent on critically ill patients receiving CRRT in order to characterize drug pharmacokinetics and optimize dosing strategies in patients on CRRT.

Topics & conditions

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Ketamine

Keywords

AntiepilepticsContinuous Renal Replacement TherapyAcute Kidney InjuryRenal InsufficiencyRenal FailurePharmacokinetics

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