Clinical trial

Psilocybin in Chronic Low Back Pain and Depression

Johns Hopkins UniversityRecruitingPhase 1Started Apr 22, 202440 enrolledUnited StatesNCT06355414

Abstract

This study seeks to provide insight on psilocybin's effects on mechanisms of chronic pain among patients with co-morbid chronic low back pain and depression (CLBP+D). Participants will receive either a single high-dose of psilocybin (25mg absolute dose) or methylphenidate (40mg absolute dose). Participants will be asked to complete assessments of pain, depressive symptoms, and more general questionnaires regarding the participants experiences during the experimental sessions and the associated enduring effects.

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

PsilocybinDepressionPain

Keywords

Chronic Low-back PainChronic Low-back Pain

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