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Clinical trial

Competition With Striatal [11C]ORM-13070 Binding by Atipamezole and Endogenous Noradrenaline

University of TurkuCompletedPhase 1Started Sep 1, 201110 enrolledFinlandNCT01435213

Abstract

The purpose of this study is to validate \[11C\]ORM-13070 as an alpha2C-adrenoceptor imaging agent for human positron emission tomography (PET) studies of brain alpha2C-adrenoceptor occupancy.

Topics & conditions

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Ketamine

Keywords

alpha2-adrenoceptorreceptor occupancypositron emission tomography[11C]ORM-13070striatumbrainnoradrenalinenorepinephrineendogenousbindingValidation studiesHealthy

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