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Clinical trial

Subanesthetic Esketamine for Hemodynamic Stability and Recovery in Elderly Thoracic Surgery Patients

Hebei Medical University Fourth HospitalCompletedStarted Jun 1, 2023230 enrolledChinaNCT07064408

Abstract

This retrospective study evaluated the effects of a subanesthetic dose of esketamine (0.25 mg/kg) on intraoperative hemodynamic stability and postoperative recovery quality in elderly patients (aged 65-75) undergoing thoracic surgery under general anesthesia. A total of 230 patients were included and randomly assigned to receive either esketamine or placebo during anesthesia induction. Key outcomes included blood pressure and heart rate stability, catecholamine levels, recovery time, incidence of adverse events such as delirium or nausea, and opioid use.

Topics & conditions

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Ketamine

Keywords

EsketamineHemodynamic stabilityAnesthesia inductionRecovery qualityElderly patientsThoracic surgeryPostoperative outcomesRandomized controlled trialPerioperative managementHemodynamic InstabilityPostoperative RecoveryThoracic SurgeryAnesthesia, GeneralElderly Patients

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