Peer-reviewed articleOpen access
Is psilocybin an effective antidepressant and what is its Mechanism of action?
Abstract
Goodwin et al.<sup>1</sup> report a single 25 mg dose of psilocybin has an antidepressant effect short-term in medication-resistant depression. Unanswered questions include drug blood level as a guide to dose, psychedelic effects relationship to antidepressant benefit, and potential suicide risk of psilocybin.
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