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Clinical trial

Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery

Peking University First HospitalRecruitingPhase 4Started Jan 5, 2026316 enrolledChinaNCT07308756

Abstract

For patients after surgery, quality of recovery has significant impacts on the prognosis, quality of life, and rational allocation of medical resources. Dexmedetomidine and esketamine have each been used during the perioperative period and improved postoperative analgesia and subjective sleep quality. This 2x2 factorial trial is designed to explore the effects of dexmedetomidine, esketamine, and their combination on the quality of recovery in patients recovering from surgery under general anesthesia.

Topics & conditions

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Ketamine

Keywords

General anesthesiaSurgeryDexmedetomidineEsketamineQuality of recoveryGeneral AnesthesiaSurgeryDexmedetomidineEsketamineQuality of Recovery

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