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Clinical trial

Psilocybin Administration With 5-HT1a Blockade

Johns Hopkins UniversityRecruitingEarly Phase 1Started Aug 12, 202618 enrolledUnited StatesNCT07565493

Abstract

The purpose of this study is to assess the effects of 5-HT1A receptor blockade on the acute subjective effects of psilocybin, as measured through subjective survey measures and acute electroencephalography (EEG). Further, the investigators will assess the effects of psilocybin on post-acute sleep and dreaming through the use of sleep EEG and sleep and dream diaries.

Topics & conditions

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Psilocybin

Keywords

SleepDreamingEEG5-HT1AAntagonismAltered state of consciousnessSubjective experienceSerotonin receptorPsychedelicPsychedelic Effects in Healthy Volunteers

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