Ketamine Treatment for Alcohol Use Disorder: A Systematic Review
Abstract
Alcohol use disorder is a chronic, recurrent condition which demonstrates significant heterogeneity in treatment response to first-line agents. Ketamine may have a therapeutic role in substance use disorders, however the research on this topic is limited. The objective of this systematic review is to qualitatively synthesize the current evidence of ketamine treatment for alcohol use disorder and evaluate its efficacy. A systematic review of Medline, PsycINFO, CINAHL, Cochrane Library, and Google Scholar was performed to identify completed human studies in English or Spanish. Data was descriptively summarized and presented in tables and text via narrative synthesis methodology. Risk of bias was measured with Cochrane Collaboration tools and a case series quality assessment tool.
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