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Clinical trial

Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study

University Hospital, Basel, SwitzerlandCompletedEarly Phase 1Started Oct 1, 201324 enrolledSwitzerlandNCT01951508

Abstract

The purpose of this study is to investigate effects of methylphenidate, modafinil, and 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") on emotion-processing and cognitive performance using functional magnetic resonance imaging (fMRI) techniques. The primary hypothesis is that these psychostimulants differentially affect processing of emotional stimuli and potentially leading to alterations in social cognition and behavior.

Topics & conditions

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MDMAAddiction

Keywords

MethylphenidateModafinilfMRIemotion-processingsocial cognitionHealthySubstance-related DisorderMood Disorder

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