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Effects of serotonergic psychedelics in non-clinical settings : a systematic review and meta-analysis

OSFOct 26, 2025

Abstract

This work will systematically review all published studies on the effects of psychedelics in non-clinical settings. Where sufficient data are available, a meta-analysis will be conducted on relevant outcomes. The review aims to assess potential improvements in mental health (e.g., depression, anxiety, substance use) and changes in psychological functioning and personality traits (e.g., creativity, openness, social functioning).

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

PsychedelicsDepressionAnxietyAddiction

Keywords

mental health

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