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Clinical trial

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

National Institute of Allergy and Infectious Diseases (NIAID)RecruitingPhase 3Started Aug 17, 2020156 enrolledUnited StatesNCT04047628

Abstract

This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio. All participants will be followed for 72 months after randomization (Day 0, Visit 0).

Topics & conditions

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DMTDepression

Keywords

Treatment-Resistant Relapsing Multiple Sclerosis (MS)Autologous Hematopoietic Stem Cell Transplantation (AHSCT)Autologous Peripheral Blood Stem Cells (PBMCs) GraftBest Available Therapy (BAT)Disease-Modifying Therapy (DMT)BAT DMTRelapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis

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