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Preregistration

Psilocybin-Assisted Therapy for Common Mental Health Disorders and their Comorbid Presentations: A Scoping Review

OSFJun 15, 2026

Abstract

This project is a scoping review examining the current evidence base for psilocybin-assisted therapy across depression, anxiety disorders, substance use disorders, and their comorbid presentations. The review aims to map the scope of existing research, summarise reported therapeutic outcomes, and evaluate the methodological quality of the evidence base. The full study rationale, objectives, eligibility criteria, search strategy, and planned methods are provided in the attached protocol document.

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

PsilocybinDepressionAnxietyAddiction

Keywords

Common Mental Health DisordersComorbidityEvidence SynthesisMental HealthProtocolPsilocybin-assisted therapyPsychiatryScoping ReviewSubstance use

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