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Clinical trial

Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy

Fauji Foundation HospitalCompletedStarted Jul 1, 202580 enrolledPakistanNCT07273851

Abstract

This randomized controlled trial will compare two anesthetic agents, propofol and ketofol (a combination of propofol and ketamine), in patients undergoing electroconvulsive therapy (ECT). Propofol is commonly used but may lower blood pressure, while ketofol may help maintain more stable cardiovascular function. The study will evaluate changes in systolic blood pressure following ECT when either propofol or ketofol is used for anesthesia induction. A total of 80 adult patients will be enrolled and randomly assigned to one of the two treatment groups. Findings may guide anesthesiologists in selecting the safest and most effective induction agent for ECT.

Topics & conditions

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KetamineDepression

Keywords

Propofol Ketofol Electroconvulsive Therapy Anesthesia Hemodynamic StabilityMajor Depressive Disorder

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