Brain structure and activity predicting cognitive maturation in adolescence
Abstract
BIDS_Garin_Zhu_Constantinidis.zip: Longitudinal MRI dataset of 8 macaques monkeys scanned every 3 months (11 sessions) at Wake Forest Universtity This dataset includes: anatomical MRI (T1, T2, T2 Flair), fonctional MRI, and fmap Structural MRIs were collected from the monkeys of cohort A every 3 months from 2.8 years (34 months) of age to 5.8 years (69 months) of age. In preparation for the MRI scan, anesthesia was induced using ketamine (5–10mg/kg) and dexmedetomidine (0.015mg/kg), and was maintained using isoflurane. The animals were intubated and artificially ventilated at about 20 breaths per minute. Expired CO2 was monitored and maintained between 35 and 45 mmHg. Animals were scanned under isoflurane anesthesia at 1%–1.5%. Heart rate and oxygen saturation levels were monitored using a pulse oximeter. Their body temperature was maintained using warm blankets. The MRI system was a 3 Tesla Siemens MAGNETOM Skyra (Siemens Healthcare, Erlangen, Germany). Anatomical images were acquired using a T1-weighted MPRAGE sequence: TR = 2700 ms, TE = 3.32 ms, inversion time = 880, FOV = 128 × 128 mm, 192 slices of 0.5 mm thickness, resolution = 0.5 mm isotropic. Resting state time series data were also acquired using a multiband EPI sequence: TR = 700 ms, TE = 32.0 ms, flip angle = 52°, repetitions = 700, FOV = 128 × 128 mm, 32 slices, resolution = 2 mm isotropic. Data are formated in standard BIDS format cog_mat_ado_release.zip: The code and used to process the results and generate the figures (also available in CodeOcean: https://codeocean.com/capsule/7858389/tree)
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