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Clinical trial

Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)

University Hospital, Basel, SwitzerlandCompletedStarted Jan 1, 201116 enrolledSwitzerlandNCT01270672

Abstract

The purpose of this study is to determinate the effect of a pre-treatment with carvedilol, a alpha- and beta-adrenergic receptor blocker, on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The investigators hypothesize that carvedilol will attenuate the cardiovascular and subjective response to MDMA.

Topics & conditions

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MDMAAddiction

Keywords

carvedilolnorepinephrinealpha - beta receptorEcstasystimulantMood DisorderSubstance-Related DisordersAmphetamine-Related Disorders

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